DCTN5 and CHP2

		DCTN5	CHP2
Description		dynactin subunit 5	calcineurin like EF-hand protein 2
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Nucleoplasm Chromosome Cytoplasm Centrosome Cytosol Cytoskeleton Dynactin Complex Nuclear Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Ventricular Septum Development Aorta Development Coronary Vasculature Development	Positive Regulation Of Cell Population Proliferation Positive Regulation Of Phosphatase Activity Protein Transport Regulation Of Protein Import Into Nucleus Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Calcium Ion
Pathways		MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Bipolar disorder ( 17554300)	Daytime nap ( 33568662)
Interacting Genes		5 interacting genes: DYNLL1 FATE1 NINL PMEPA1 RBPMS	6 interacting genes: MDFI SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5
Entrez ID		84516	63928
HPRD ID		14551	14259
Ensembl ID		ENSG00000166847	ENSG00000166869
Uniprot IDs		Q9BTE1	O43745
PDB IDs		5NW4	2BEC
Enriched GO Terms of Interacting Partners?			Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity Sodium Ion Import Across Plasma Membrane Regulation Of Cellular PH Regulation Of Intracellular PH Antiporter Activity Inorganic Cation Import Across Plasma Membrane Regulation Of PH Sodium Ion Transmembrane Transport Import Across Plasma Membrane Potassium Ion Transmembrane Transport Proton Transmembrane Transport Potassium Ion Transport Sodium Ion Transport Intracellular Monoatomic Cation Homeostasis Intracellular Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Intracellular Chemical Homeostasis Metal Ion Transport Import Into Cell Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Cellular Homeostasis Inorganic Ion Transmembrane Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Chemical Homeostasis Apical Plasma Membrane Monoatomic Ion Transport Transmembrane Transport Homeostatic Process Recycling Endosome Membrane Regulation Of The Force Of Heart Contraction By Cardiac Conduction Cation-transporting ATPase Complex Regulation Of Biological Quality Transporter Complex Transepithelial Ammonium Transport Positive Regulation Of The Force Of Heart Contraction Glandular Epithelial Cell Development Regulation Of Cardiac Muscle Cell Membrane Potential Protein Phosphatase 2B Binding Neuron Spine Dynactin Complex Gastric Acid Secretion Cardiac Muscle Cell Contraction Positive Regulation Of Action Potential Arrestin Family Protein Binding Cellular Response To Antibiotic Basolateral Plasma Membrane
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