REEP6 and TMEM259

		REEP6	TMEM259
Description		receptor accessory protein 6	transmembrane protein 259
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Inner Segment Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding
	Biological Process	Endoplasmic Reticulum Organization Regulation Of Intracellular Transport Detection Of Light Stimulus Involved In Visual Perception	Response To Endoplasmic Reticulum Stress Positive Regulation Of ERAD Pathway
Pathways
Drugs
Diseases
GWAS			Eosinophil percentage of granulocytes ( 27863252) Red cell distribution width ( 27863252)
Interacting Genes		46 interacting genes: AQP6 ARL6IP1 ATP5PF BIK CD79A CDC37 CERT1 COQ8A CYB561 CYB5R3 EBAG9 FHIP1B GJA8 GORASP2 GPR152 HMBOX1 HSD17B13 KRTAP3-1 LEPROTL1 LITAF LMNA LNX1 MIEF2 NDRG4 NTAQ1 PICK1 PTPN9 RPS20 SDCBP SLC30A8 SNX1 SNX11 SNX15 SNX8 SPG21 STING1 SYT16 TIMMDC1 TLCD4 TMED8 TMEM143 TMPPE TNS2 TXN2 WIPI2 ZFYVE21	2 interacting genes: ADRB2 ARSL
Entrez ID		92840	91304
HPRD ID		16629	12710
Ensembl ID		ENSG00000115255	ENSG00000182087
Uniprot IDs		A0A1L5BXV2 Q96HR9	B3KTL0 Q4ZIN3
PDB IDs
Enriched GO Terms of Interacting Partners?		Lipid Binding Establishment Of Protein Localization Identical Protein Binding Membrane	Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Response To Psychosocial Stress Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Norepinephrine Binding Positive Regulation Of Lipophagy AMPA Selective Glutamate Receptor Signaling Pathway Beta2-adrenergic Receptor Activity Positive Regulation Of Autophagosome Maturation Heat Generation Diet Induced Thermogenesis Adrenergic Receptor Activity Arylsulfatase Activity Adenylate Cyclase Binding Negative Regulation Of Smooth Muscle Contraction Negative Regulation Of Multicellular Organism Growth Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Autophagosome Maturation Positive Regulation Of CAMP/PKA Signal Transduction Negative Regulation Of Muscle Contraction Neuronal Dense Core Vesicle Adrenergic Receptor Signaling Pathway Negative Regulation Of Systemic Arterial Blood Pressure Detection Of Light Stimulus Involved In Visual Perception Adaptive Thermogenesis Bone Resorption Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Brown Fat Cell Differentiation Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Excitatory Postsynaptic Potential Temperature Homeostasis Positive Regulation Of Protein-containing Complex Disassembly Clathrin-coated Vesicle Membrane Golgi Stack Regulation Of CAMP/PKA Signal Transduction Potassium Channel Regulator Activity Ligand-gated Ion Channel Signaling Pathway Regulation Of Systemic Arterial Blood Pressure Response To Cold Positive Regulation Of Bone Mineralization Smooth Muscle Contraction Vasodilation Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Glutamate Receptor Signaling Pathway Cellular Response To Amyloid-beta Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Ossification Endosome To Lysosome Transport Negative Regulation Of Blood Pressure
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