ATPAF2 and ATP5A1

Number of citations of the paper that reports this interaction (PMID 11410595)
12

Data Source:
HPRD (two hybrid)

		ATPAF2	ATP5A1
Gene Name		ATP synthase mitochondrial F1 complex assembly factor 2	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Nuclear Speck	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Plasma Membrane COP9 Signalosome Membrane Proton-transporting ATP Synthase Complex, Catalytic Core F(1) Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein Binding ATP Binding ATPase Activity Transmembrane Transporter Activity MHC Class I Protein Binding Poly(A) RNA Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Proton-transporting ATP Synthase Complex Assembly	Negative Regulation Of Endothelial Cell Proliferation Lipid Metabolic Process ATP Biosynthetic Process Embryo Development ATP Hydrolysis Coupled Proton Transport Respiratory Electron Transport Chain Mitochondrial ATP Synthesis Coupled Proton Transport Cellular Metabolic Process Small Molecule Metabolic Process
Pathways			Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Mitochondrial protein import The citric acid (TCA) cycle and respiratory electron transport Formation of ATP by chemiosmotic coupling
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: APP ATP5A1 ATP5B DDIT3 EBF1 EWSR1 IKZF3 KRT40 LNX1 LRRFIP2 LZTS2 MAGEA6 PAK7 PKP4 PRDM14 RAD54B REL RPIA SORBS2 SPG21 TP53BP2 TRIM23 TRIM27	13 interactors: AIMP1 APP ATP5B ATP5C1 ATPAF1 ATPAF2 CSNK2A1 RPS6KB2 SHBG YWHAB YWHAG YWHAQ YWHAZ
Entrez ID		91647	498
HPRD ID		10599	01258
Ensembl ID		ENSG00000171953	ENSG00000152234
Uniprot IDs		Q8N5M1	B4DY56 K7ENP3 P25705
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitochondrial ATP Synthesis Coupled Proton Transport Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process ATP Synthesis Coupled Proton Transport Cellular Nitrogen Compound Metabolic Process ATP Biosynthetic Process Negative Regulation Of Determination Of Dorsal Identity Histone H3-R26 Methylation Inner Cell Mass Cell Fate Commitment Nitrogen Compound Metabolic Process ATP Hydrolysis Coupled Proton Transport Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Regulation Of Transcription Involved In Anterior/posterior Axis Specification Intracellular Transport Wnt Signaling Pathway Purine Ribonucleoside Monophosphate Biosynthetic Process Regulation Of Signal Transduction Collateral Sprouting In Absence Of Injury Nucleoside Triphosphate Biosynthetic Process Ribose Phosphate Metabolic Process Transcription, DNA-templated Ribonucleoside Monophosphate Biosynthetic Process Pentose-phosphate Shunt, Non-oxidative Branch	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Apoptotic Process Programmed Cell Death Cell Death Death Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Intracellular Transport Positive Regulation Of Intracellular Transport Apoptotic Signaling Pathway Establishment Of Localization In Cell Mitochondrial ATP Synthesis Coupled Proton Transport Positive Regulation Of Organelle Organization Protein Targeting Mitochondrial Transport Regulation Of Intracellular Transport Regulation Of Organelle Organization Cellular Localization ATP Synthesis Coupled Proton Transport ATP Biosynthetic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Phosphorylation Chemotaxis Positive Regulation Of Cell Death Phosphate-containing Compound Metabolic Process Locomotion Positive Regulation Of Signal Transduction Regulation Of Establishment Of Protein Localization Defense Response Positive Regulation Of Transport Primary Spermatocyte Growth Regulation Of Protein Localization Regulation Of Apoptotic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Negative Regulation Of Cellular Protein Metabolic Process Movement Of Cell Or Subcellular Component Membrane Organization Regulation Of Cell Death Developmental Cell Growth Nucleoside Triphosphate Biosynthetic Process Negative Regulation Of Protein Metabolic Process Axon Guidance Intracellular Protein Transport Synaptic Growth At Neuromuscular Junction Ribonucleoside Monophosphate Biosynthetic Process
Tagcloud ?			2de angustifolia apoa1 bioinformatics caliber david diminishing dysregulated histopathology hspa5 kegg la lavandula lavender le likewise ontology operate pharmaceutically prdx2 predictedinteractions scrutinized searching slowing snca string sum tof
Tagcloud (Difference) ?			2de angustifolia apoa1 bioinformatics caliber david diminishing dysregulated histopathology hspa5 kegg la lavandula lavender le likewise ontology operate pharmaceutically prdx2 predictedinteractions scrutinized searching slowing snca string sum tof
Tagcloud (Intersection) ?