ATPAF2 and CTIF

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATPAF2	CTIF
Description		ATP synthase mitochondrial F1 complex assembly factor 2	cap binding complex dependent translation initiation factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Cytosol Membrane Nuclear Speck	Cytoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	RNA Binding Protein Binding Translation Activator Activity
	Biological Process	Mitochondrial Proton-transporting ATP Synthase Complex Assembly Proton-transporting ATP Synthase Complex Assembly	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Translation Regulation Of Translational Initiation Positive Regulation Of Translation
Pathways
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Schizophrenia ( 25056061 28991256 29483656) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Automobile speeding propensity ( 30643258) Ceramide levels (C22:0) ( 32489964) Ceramide levels (C24:0) ( 32489964) Height ( 31562340) Hematocrit ( 32888494) Hemoglobin ( 32888494) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Iris heterochromicity ( 30895295) Large HDL particle concentration ( 29084231) Lumbar spine bone mineral density (integral) ( 27476799) Mean diameter of HDL particles ( 29084231) Phospholipid levels in large HDL ( 29084231) Red blood cell count ( 27863252 32888494) Response to carboplatin in ovarian cancer (MTT IC50) ( 27047539) Rheumatoid arthritis ( 30891314) White blood cell count ( 32888494)
Interacting Genes		72 interacting genes: AKAP8L APP ATP5F1A ATP5F1B BEGAIN CDC14A CDK2AP1 CEP57 CFAP206 CFAP68 CIMIP2B CRTC2 CTIF CYSRT1 DDIT3 DLGAP4 EBF1 EBF3 EIF4G1 EWSR1 FCHSD2 FNTB GOLGA6L9 IKZF3 INCA1 KRT34 KRT40 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-2 KRTAP6-3 LGALS9B LNX1 LRRFIP2 LURAP1L LZTS2 MAGEA6 MEDAG MIF4GD NME4 PAK5 PKP4 POLR2J3 POLR3F POLR3H PPP1R16B PRDM14 PRDM6 RAD54B RBM48 RCN1 REL RPH3AL RPIA SAXO4 SORBS2 SPATC1L TCHP TFIP11 TP53BP2 TRIM23 TRIM27 UBAP2 VWC2 WASHC1 ZFP90 ZNF19 ZNF23 ZNF35 ZNF426 ZNF655	8 interacting genes: ATPAF2 ATXN7L2 DCTN1 EEF1A1 HEXIM2 HOOK3 RECK SPG21
Entrez ID		91647	9811
HPRD ID		10599	11083
Ensembl ID		ENSG00000171953	ENSG00000134030
Uniprot IDs		Q8N5M1	O43310
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Intermediate Filament	Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Microtubule Anchoring Nuclear Migration Nucleus Localization Response To Epidermal Growth Factor
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