MTMR9 and MTMR6

Number of citations of the paper that reports this interaction (PMID 12890864)
22

Data Source:
BioGRID (two hybrid, pull down, affinity chromatography technology)
HPRD (in vitro, in vivo)

		MTMR9	MTMR6
Gene Name		myotubularin related protein 9	myotubularin related protein 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nuclear Envelope Cytoplasm Cytosol
	Molecular Function	Protein Binding Phosphatase Activity Enzyme Regulator Activity	Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Calcium-activated Potassium Channel Activity
	Biological Process	Dephosphorylation Regulation Of Catalytic Activity	Protein Dephosphorylation Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Peptidyl-tyrosine Dephosphorylation Small Molecule Metabolic Process Potassium Ion Transmembrane Transport
Pathways			Synthesis of PIPs at the plasma membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS		Retinal vascular caliber ( 21060863)
Protein-Protein Interactions		11 interactors: EMILIN1 EWSR1 KDM1A LNX1 MOS MTMR6 MTMR7 MTMR8 NMI SPG21 VAC14	6 interactors: AMOTL2 MTMR9 MTUS2 NMI RARG TRIM27
Entrez ID		66036	9107
HPRD ID		09377	11946
Ensembl ID		ENSG00000104643	ENSG00000139505
Uniprot IDs		Q96QG7	Q9Y217
PDB IDs			2YF0
Enriched GO Terms of Interacting Partners?		Phosphatidylinositol Biosynthetic Process Peptidyl-tyrosine Dephosphorylation Glycerophospholipid Biosynthetic Process Phosphatidylinositol Metabolic Process Phospholipid Biosynthetic Process Protein Dephosphorylation Glycerophospholipid Metabolic Process Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle Regulation Of Primitive Erythrocyte Differentiation Glycerolipid Metabolic Process Phospholipid Metabolic Process Dephosphorylation Cellular Protein Modification Process Negative Regulation Of Meiotic Cell Cycle Phase Transition Lipid Biosynthetic Process Establishment Of Meiotic Spindle Localization Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation	Growth Plate Cartilage Chondrocyte Growth Negative Regulation Of Interleukin-2 Secretion Growth Plate Cartilage Chondrocyte Development Harderian Gland Development Chondrocyte Hypertrophy Growth Plate Cartilage Chondrocyte Differentiation Negative Regulation Of Calcium Ion Import Wnt Signaling Pathway Retinal Pigment Epithelium Development Interferon-gamma Secretion Lacrimal Gland Development Regulation Of Cellular Component Size
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