TRIM41 and AEN

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRIM41	AEN
Gene Name		tripartite motif containing 41	apoptosis enhancing nuclease
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm	Nucleus Nucleoplasm Nucleolus Nuclear Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Ligase Activity	Nucleic Acid Binding Exonuclease Activity
	Biological Process	Protein Ubiquitination	Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		58 interactors: AEN AES AKTIP APP BRAP CEP44 CHD2 CSNK2A2 EHHADH FAM124A FRA10AC1 GPATCH2L IKBKG KIFC3 KRTAP10-9 MAGEH1 MEOX2 MORF4L1 MPP3 NCK2 NEDD4L PHC2 PHF7 PRKCA PRKCB PUS7L RNPS1 SORBS3 SRPK2 TOP3B TRAIP TRIM17 TRIM26 TRIM4 TRIM52 UBC UBE2D2 UBE2I ZBTB24 ZBTB38 ZBTB8A ZFP2 ZFP64 ZNF138 ZNF250 ZNF26 ZNF263 ZNF264 ZNF266 ZNF329 ZNF417 ZNF473 ZNF490 ZNF564 ZNF587 ZNF670 ZSCAN21 ZSCAN26	33 interactors: AAMP AES EMD EXOSC8 GNPTAB HOMEZ IKZF1 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SSX2IP TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF473
Entrez ID		90933	64782
HPRD ID		15558	08573
Ensembl ID		ENSG00000146063	ENSG00000181026
Uniprot IDs		Q8WV44	Q8WTP8
PDB IDs		2EGM
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Gene Expression Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Cellular Metabolic Process Biosynthetic Process Regulation Of Cellular Process Metabolic Process Histone H3-T6 Phosphorylation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell Death Death Regulation Of Transcription From RNA Polymerase II Promoter Protein Ubiquitination Apoptotic Process Protein Modification By Small Protein Conjugation Programmed Cell Death Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Cellular Process Innate Immune Response Positive Regulation Of Cell Cycle TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of MRNA Splicing, Via Spliceosome MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Glucose Transport Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Regulation Of MRNA Processing Negative Regulation Of Cellular Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of RNA Splicing	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Negative Regulation Of Viral Release From Host Cell Regulation Of RNA Splicing MRNA Metabolic Process Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of Alternative MRNA Splicing, Via Spliceosome Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process MRNA Processing Positive Regulation Of Neutrophil Differentiation Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Protein Binding Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Interleukin-2 Secretion Positive Regulation Of Androgen Secretion Regulation Of Viral Transcription Cellular Metabolic Process RNA Processing Negative Regulation Of Viral Process Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Estrogen Receptor Binding Regulation Of Wnt Signaling Pathway Response To Interleukin-1 Positive Regulation Of Anoikis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Binding Negative Regulation Of Nucleic Acid-templated Transcription Histone MRNA 3'-end Processing RNA Splicing Biosynthetic Process Intraciliary Transport Involved In Cilium Morphogenesis
Tagcloud ?		actb ap1s1 api5 calculating crossbred csn1s2 fabp3 gilts icg lactation ltf mined mrpl39 mtg1 normalization parturition pcsk2 ppp2r5b primiparous ptbp1 qpcr qtrt1 rps15a scd tmem24 underscore uxt vabp vapb	abrupt appearing black characteristically circumferential compromised corrosive defenses demarcation duodenal endoscopically endoscopy esophageal esophagus gaining gastroesophageal ge globe hemorrhage hypoalbuminemia insult malnourishment morbidities multifactorial reflection sharp stricture striking universal
Tagcloud (Difference) ?		actb ap1s1 api5 calculating crossbred csn1s2 fabp3 gilts icg lactation ltf mined mrpl39 mtg1 normalization parturition pcsk2 ppp2r5b primiparous ptbp1 qpcr qtrt1 rps15a scd tmem24 underscore uxt vabp vapb	abrupt appearing black characteristically circumferential compromised corrosive defenses demarcation duodenal endoscopically endoscopy esophageal esophagus gaining gastroesophageal ge globe hemorrhage hypoalbuminemia insult malnourishment morbidities multifactorial reflection sharp stricture striking universal
Tagcloud (Intersection) ?