TGIF2LY and MBIP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TGIF2LY	MBIP
Description		TGFB induced factor homeobox 2 like Y-linked	MAP3K12 binding inhibitory protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Mitotic Spindle ATAC Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Kinase Inhibitor Activity Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Regulation Of Embryonic Development Positive Regulation Of JNK Cascade Regulation Of Cell Division Regulation Of Cell Cycle
Pathways			HATs acetylate histones Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS			Hypertension ( 31513605) Thyroid cancer ( 22267200) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 25743335 32769997)
Interacting Genes		3 interacting genes: MBIP NAB2 PCBD2	47 interacting genes: BFSP2 CALM1 CCDC85B CCNC CEP63 COPS4 DGCR6 DGCR6L DIP2A DRC7 EPB41L3 EXOC8 FXR1 FXR2 ING5 KAT14 KLC3 LIMS1 LMNB1 LMO2 LMO3 MAP3K12 MAPK6 MCM7 MIS18A MOAP1 MYD88 NDEL1 NINL PIK3R3 PLEKHF2 POLR1C PPFIA1 RAP1GDS1 RAPGEF1 SHANK3 SMARCB1 STX11 TGIF2LY TRIM55 TRIM63 TSC1 TXLNA TXLNB VPS28 VTA1 WDR5
Entrez ID		90655	51562
HPRD ID		18512	14368
Ensembl ID		ENSG00000176679	ENSG00000151332
Uniprot IDs		Q8IUE0	B2RCV0 Q9NS73
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription By RNA Polymerase III Schwann Cell Differentiation 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Tetrahydrobiopterin Biosynthetic Process Tetrahydrobiopterin Metabolic Process ATAC Complex Pteridine-containing Compound Biosynthetic Process Endochondral Ossification Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase III Diol Metabolic Process Pteridine-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Protein Kinase Inhibitor Activity	Positive Regulation Of Long-term Neuronal Synaptic Plasticity Protein Binding Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Long-term Neuronal Synaptic Plasticity Nuclear Pore Localization Endosome Organization Positive Regulation Of GTPase Activity Cytoplasm Organelle Organization Positive Regulation Of Hydrolase Activity
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