SSB and GZMH

Number of citations: 0 (PubMedID 19039329)
Data Source: BioGRID (enzymatic study)

		SSB	GZMH
Name		small RNA binding exonuclease protection factor La	granzyme H
Structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule Ribonucleoprotein Complex	Extracellular Space Lysosome Membrane Cytolytic Granule
	Molecular Function	TRNA Binding Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Poly(U) RNA Binding Sequence-specific MRNA Binding	Serine-type Endopeptidase Activity Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	TRNA 5'-leader Removal RNA Processing TRNA Modification TRNA Export From Nucleus TRNA Processing Histone MRNA Metabolic Process TRNA 3'-end Processing Positive Regulation Of Translation Nuclear Histone MRNA Catabolic Process IRES-dependent Viral Translational Initiation Protein Localization To Cytoplasmic Stress Granule	Proteolysis Apoptotic Process Killing Of Cells Of Another Organism Protein Maturation
Pathways		RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation	Metabolism of Angiotensinogen to Angiotensins Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
GWAS		Common carotid intima-media thickness in HIV infection ( 29206233 ) Fasting glucose change (long-term) ( 31263163 ) Glomerular filtration rate in diabetes ( 29703844 )	No GWAS studies recorded
Novel Interactors		1 novel interactors: NAT8	None recorded
Interacting Genes		14 interacting genes: APP CDC42 CEBPA CSNK2A1 CSNK2B GZMH H19 HMGA1 IL7R NCL OGT PTEN SPIB SPP1	1 interacting genes: SSB
Entrez ID		6741	2999
HPRD ID		00168	00290
Ensembl ID		ENSG00000138385	ENSG00000100450
Uniprot IDs		P05455	P20718
PDB IDs		1OWX 1S79 1S7A 1YTY 1ZH5 2VOD 2VON 2VOO 2VOP	3TJU 3TJV 3TK9 4GAW
GO Terms Enriched among Interactors		Regulation Of Proteolysis Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Macromolecule Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Neuron Projection Organization Positive Regulation Of Macromolecule Biosynthetic Process Macrophage Differentiation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Protein Catabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of RNA Biosynthetic Process Regulation Of Cell Population Proliferation Positive Regulation Of DNA-templated Transcription Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of RNA Metabolic Process Response To Cytokine Response To Peptide Positive Regulation Of Nucleobase-containing Compound Metabolic Process Dendritic Spine Morphogenesis PML Body Negative Regulation Of Protein Metabolic Process Regulation Of Growth Regulation Of Protein Metabolic Process Mononuclear Cell Differentiation Negative Regulation Of Protein Catabolic Process Sin3-type Complex Regulation Of Macromolecule Metabolic Process Positive Regulation Of Signal Transduction Molecular Function Activator Activity Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Proteolysis Leukocyte Differentiation Myeloid Leukocyte Differentiation Response To Nutrient PcG Protein Complex Regulation Of Gene Expression Negative Regulation Of Cell Population Proliferation Amyloid Fibril Formation Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Excitatory Postsynaptic Potential	Nuclear Histone MRNA Catabolic Process TRNA Export From Nucleus Histone MRNA Catabolic Process TRNA Transport Protein Localization To Cytoplasmic Stress Granule IRES-dependent Viral Translational Initiation TRNA 5'-leader Removal TRNA 3'-end Processing TRNA 5'-end Processing Sequence-specific MRNA Binding Poly(U) RNA Binding Histone MRNA Metabolic Process RNA Export From Nucleus TRNA Binding RNA 3'-end Processing TRNA Modification Cytoplasmic Stress Granule Nuclear-transcribed MRNA Catabolic Process TRNA Processing Nuclear Export Viral Process RNA Modification MRNA Catabolic Process Positive Regulation Of Translation RNA Transport Chromosome, Telomeric Region TRNA Metabolic Process RNA Catabolic Process Nucleobase-containing Compound Transport Nuclear Transport Nucleocytoplasmic Transport MRNA Binding