SSB and H19

Number of citations of the paper that reports this interaction (PubMedID 37298108)
45

Data Source:
BioGRID (unspecified method)

		SSB	H19
Description		small RNA binding exonuclease protection factor La	H19 imprinted maternally expressed transcript
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule Ribonucleoprotein Complex
	Molecular Function	TRNA Binding Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Poly(U) RNA Binding Sequence-specific MRNA Binding
	Biological Process	TRNA 5'-leader Removal RNA Processing TRNA Modification TRNA Export From Nucleus TRNA Processing Histone MRNA Metabolic Process TRNA 3'-end Processing Positive Regulation Of Translation Nuclear Histone MRNA Catabolic Process IRES-dependent Viral Translational Initiation Protein Localization To Cytoplasmic Stress Granule
Pathways		RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases			Russell-Silver syndrome; Silver-Russell syndrome Beckwith-Wiedemann syndrome
GWAS		Common carotid intima-media thickness in HIV infection ( 29206233) Fasting glucose change (long-term) ( 31263163) Glomerular filtration rate in diabetes ( 29703844)	Celiac disease ( 23936387) Creatinine levels ( 29403010) Diastolic blood pressure ( 27841878) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) DNA methylation (parent-of-origin) ( 23725790) DNA methylation (variation) ( 23725790) Estimated glomerular filtration rate ( 30604766) Glomerular filtration rate ( 29403010) Hypertension ( 30487518) Pulse pressure ( 27841878) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 27841878 28135244) Systolic blood pressure (cigarette smoking interaction) ( 29455858)
Interacting Genes		14 interacting genes: APP CDC42 CEBPA CSNK2A1 CSNK2B GZMH H19 HMGA1 IL7R NCL OGT PTEN SPIB SPP1	21 interacting genes: BCLAF1 DDX5 DSP ESRP1 FMR1 IFIT5 ILF2 MYO1D NSD2 PCCA PCCB PPP1R3E PRKRA SERBP1 SRSF10 SRSF8 SRSF9 SSB STON2 TPM1 U2SURP
Entrez ID		6741	283120
HPRD ID		00168
Ensembl ID		ENSG00000138385	ENSG00000130600
Uniprot IDs		P05455
PDB IDs		1OWX 1S79 1S7A 1YTY 1ZH5 2VOD 2VON 2VOO 2VOP
Enriched GO Terms of Interacting Partners?		Regulation Of Proteolysis Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Macromolecule Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Neuron Projection Organization Positive Regulation Of Macromolecule Biosynthetic Process Macrophage Differentiation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Protein Catabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of RNA Biosynthetic Process Regulation Of Cell Population Proliferation Positive Regulation Of DNA-templated Transcription Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of RNA Metabolic Process Response To Cytokine Response To Peptide Positive Regulation Of Nucleobase-containing Compound Metabolic Process Dendritic Spine Morphogenesis PML Body Negative Regulation Of Protein Metabolic Process Regulation Of Growth Regulation Of Protein Metabolic Process Mononuclear Cell Differentiation Negative Regulation Of Protein Catabolic Process Sin3-type Complex Regulation Of Macromolecule Metabolic Process Positive Regulation Of Signal Transduction Molecular Function Activator Activity Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Proteolysis Leukocyte Differentiation Myeloid Leukocyte Differentiation Response To Nutrient PcG Protein Complex Regulation Of Gene Expression Negative Regulation Of Cell Population Proliferation Amyloid Fibril Formation Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Excitatory Postsynaptic Potential	RNA Binding Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Binding Regulation Of RNA Splicing Nucleic Acid Binding Regulation Of MRNA Splicing, Via Spliceosome RNA Processing Regulation Of MRNA Processing Propionyl-CoA Carboxylase Activity Regulation Of MRNA Metabolic Process Poly(U) RNA Binding RNA Splicing MRNA Metabolic Process MRNA Processing Short-chain Fatty Acid Catabolic Process Ribonucleoprotein Complex SiRNA Binding Sequence-specific MRNA Binding Nuclear Speck Translation Repressor Activity Short-chain Fatty Acid Metabolic Process Nuclear-transcribed MRNA Catabolic Process Negative Regulation Of Gene Expression Regulation Of Viral Life Cycle Catalytic Complex Negative Regulation Of MRNA Splicing, Via Spliceosome Branched-chain Amino Acid Metabolic Process MRNA Catabolic Process Negative Regulation Of RNA Splicing MRNA 3'-UTR Binding Regulation Of Viral Process Negative Regulation Of Macromolecule Biosynthetic Process Nucleolus MRNA Splice Site Recognition MiRNA Processing Negative Regulation Of Biosynthetic Process RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process MiRNA Transcription Positive Regulation Of Intracellular Transport Of Viral Material Ligase Activity, Forming Carbon-carbon Bonds Nuclear Histone MRNA Catabolic Process Positive Regulation Of Heart Rate By Epinephrine Regulation Of Inner Ear Auditory Receptor Cell Fate Specification Ventricular Cardiac Muscle Tissue Morphogenesis Regulation Of Primary Metabolic Process RNA Catabolic Process Nucleic Acid Metabolic Process Protein-RNA Complex Assembly Negative Regulation Of Macromolecule Metabolic Process
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