BRSK2 and CDC25C

Number of citations of the paper that reports this interaction (PMID 15150265)
11

Data Source:
HPRD (in vitro)

		BRSK2	CDC25C
Gene Name		BR serine/threonine kinase 2	cell division cycle 25C
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Centrosome Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity ATP Binding Protein Kinase Binding Tau-protein Kinase Activity	Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding WW Domain Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Protein Phosphorylation Exocytosis Mitotic Nuclear Division Axonogenesis Peptidyl-serine Phosphorylation Establishment Of Cell Polarity Neuron Differentiation Actin Cytoskeleton Reorganization Cell Division Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Replication Mitotic Nuclear Division Regulation Of Mitotic Nuclear Division Spermatogenesis Cell Proliferation Viral Process Peptidyl-tyrosine Dephosphorylation Cell Division Regulation Of Cell Cycle
Pathways			Cyclin A/B1 associated events during G2/M transition G2/M DNA damage checkpoint G2/M Checkpoints Activation of ATR in response to replication stress Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex G2/M Transition Cell Cycle Checkpoints Mitotic G2-G2/M phases Cyclin B2 mediated events Polo-like kinase mediated events Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CDC25B CDC25C VCP WEE1	29 interactors: BRSK1 BRSK2 CCNA2 CCNB1 CDK1 CDK2 CDS1 CHEK1 CHEK2 HRAS LCK LZTS1 MAPK1 MAPK14 MAPK3 MAPK9 MARK3 NEDD4 PCNA PIN1 PKN1 PLK1 PLK3 SRC TP53 YWHAB YWHAH YWHAQ YWHAZ
Entrez ID		9024	995
HPRD ID		11611	01146
Ensembl ID		ENSG00000174672	ENSG00000158402
Uniprot IDs		B3KVE9 B4DLY3 E9PLM7 Q8IWQ3	P30307
PDB IDs			3BZI 3OP3
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Nuclear Division Cell Division Mitotic Cell Cycle Process Mitotic Cell Cycle Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Regulation Of Cell Cycle Peptidyl-tyrosine Dephosphorylation Cell Cycle Process Cellular Protein Modification Process Protein Dephosphorylation Regulation Of Cell Division Cell Cycle Retrograde Protein Transport, ER To Cytosol Regulation Of Protein Deubiquitination Protein Hexamerization Cellular Protein Metabolic Process Aggresome Assembly Regulation Of Mitotic Cell Cycle Translesion Synthesis Regulation Of Cellular Protein Metabolic Process Dephosphorylation Female Meiosis I Regulation Of Cell Cycle Process Regulation Of Protein Metabolic Process Protein Metabolic Process Postreplication Repair Regulation Of Catalytic Activity Oocyte Maturation Gamete Generation Regulation Of Protein Kinase Activity Female Meiotic Division Regulation Of Kinase Activity Sexual Reproduction Phosphate-containing Compound Metabolic Process ER-associated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cytokinesis Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Oocyte Development Oocyte Differentiation Positive Regulation Of Protein Modification Process Organelle Organization Peptidyl-amino Acid Modification Regulation Of Cytokinesis Reproduction Cellular Response To Heat	Cellular Response To Stress Cell Cycle Phosphorylation Response To Stress Cell Cycle Checkpoint Apoptotic Process G2/M Transition Of Mitotic Cell Cycle Programmed Cell Death Cell Death Death Protein Phosphorylation Regulation Of Protein Metabolic Process Intracellular Signal Transduction Positive Regulation Of Cellular Metabolic Process DNA Damage Checkpoint Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Metabolic Process Response To Abiotic Stimulus Regulation Of Mitotic Cell Cycle Positive Regulation Of Protein Phosphorylation Regulation Of Intracellular Transport Negative Regulation Of Mitotic Cell Cycle Ras Protein Signal Transduction Phosphate-containing Compound Metabolic Process Positive Regulation Of Protein Metabolic Process Cell Cycle Process Cellular Response To DNA Damage Stimulus Mitotic Cell Cycle Checkpoint Regulation Of Protein Phosphorylation Cellular Response To Stimulus Positive Regulation Of Phosphorylation Mitotic Cell Cycle Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Intrinsic Apoptotic Signaling Pathway Mitotic Cell Cycle Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Positive Regulation Of Signal Transduction Cell Aging Regulation Of Cellular Localization Regulation Of Phosphorylation Regulation Of Cellular Component Organization Apoptotic Signaling Pathway Positive Regulation Of Intracellular Transport Cellular Protein Modification Process
Tagcloud ?		aicar ampk ampkbeta blunted brsk1 c433s caax cys433 farnesylated farnesylation fertile imidazolecarboxamide knockin lkb1 lkb1c433s lkb1s431a mark4 mimetic myristoylation nuak nuak1 phenformin prenylated raises riboside s431a ser431 sik3 snf1	acetyltransferase acetyltransferases aiding ancient assembled box caf ccaat collagen disrupted facilitating gcn5 heterodimers histocompatibility lipase nf pivotal possess r2 reductase ribonucleotide transactivation transfections ubiquitous y ya yb yc
Tagcloud (Difference) ?		aicar ampk ampkbeta blunted brsk1 c433s caax cys433 farnesylated farnesylation fertile imidazolecarboxamide knockin lkb1 lkb1c433s lkb1s431a mark4 mimetic myristoylation nuak nuak1 phenformin prenylated raises riboside s431a ser431 sik3 snf1	acetyltransferase acetyltransferases aiding ancient assembled box caf ccaat collagen disrupted facilitating gcn5 heterodimers histocompatibility lipase nf pivotal possess r2 reductase ribonucleotide transactivation transfections ubiquitous y ya yb yc
Tagcloud (Intersection) ?