ATP6V0E1 and ATP6V1E1

Number of citations of the paper that reports this interaction (PubMedID 12163484)
0

Data Source:
HPRD (two hybrid)

		ATP6V0E1	ATP6V1E1
Description		ATPase H+ transporting V0 subunit e1	ATPase H+ transporting V1 subunit E1
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GO Annotations	Cellular Component	Lysosomal Membrane Endosome Membrane Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase Complex Proton-transporting V-type ATPase, V0 Domain	Vacuolar Proton-transporting V-type ATPase, V1 Domain Cytoplasm Lysosomal Membrane Endosome Cytosol Plasma Membrane Microvillus Membrane Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Clathrin-coated Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Proton-transporting Two-sector ATPase Complex, Catalytic Domain Synapse Extracellular Exosome
	Molecular Function	Protein Binding ATPase-coupled Ion Transmembrane Transporter Activity Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding
	Biological Process	Monoatomic Ion Transport Vacuolar Acidification Regulation Of Macroautophagy Transmembrane Transport Proton Transmembrane Transport	Monoatomic Ion Transport Regulation Of Macroautophagy Synaptic Vesicle Lumen Acidification Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy
Drugs		Tiludronic acid	Tiludronic acid
Diseases
GWAS		Body mass index ( 27455349) PR interval ( 32439900)
Interacting Genes		19 interacting genes: APOD ATP6V1E1 CDIPT COL8A2 CXCL16 EMP1 GPR25 KIR2DL3 MAL2 MS4A13 MS4A4A NAT8 OPRM1 PLN SYT15 SYT15B TMEM218 TMEM254 YIPF6	14 interacting genes: ALDOA ALDOB ALDOC APP ATP6V0E1 ATP6V1G1 ATP6V1G2 ATP6V1H HSPB2 MESD NHERF1 SOS1 TRAF6 XRCC6
Entrez ID		8992	529
HPRD ID		04894	00163
Ensembl ID		ENSG00000113732	ENSG00000131100
Uniprot IDs		O15342	P36543 Q53Y06
PDB IDs		6WLW 6WM2 6WM3 6WM4 7U4T 7UNF	6WLZ 6WM2 6WM3 6WM4 7U4T 7UNF
Enriched GO Terms of Interacting Partners?			Fructose-bisphosphate Aldolase Activity Proton-transporting ATPase Activity, Rotational Mechanism Fructose 1,6-bisphosphate Metabolic Process Homeostatic Process Vacuolar Proton-transporting V-type ATPase, V1 Domain Fructose Metabolic Process Extrinsic Component Of Synaptic Vesicle Membrane Cellular Homeostasis Proton-transporting V-type ATPase Complex ADP Catabolic Process Purine Ribonucleoside Diphosphate Catabolic Process Lyase Activity Glycolytic Process Growth Factor Receptor Binding Proton Transmembrane Transport ADP Metabolic Process Nucleoside Diphosphate Catabolic Process Fructose Binding Ribonucleoside Diphosphate Catabolic Process Regulation Of Macroautophagy Pyruvate Metabolic Process Cytoskeletal Protein Binding Ribonucleoside Diphosphate Metabolic Process Purine Ribonucleotide Catabolic Process Nucleoside Diphosphate Metabolic Process Purine Nucleotide Catabolic Process Intracellular Chemical Homeostasis Vacuolar Proton-transporting V-type ATPase Complex Regulation Of Phosphorus Metabolic Process Nucleotide Catabolic Process Synaptic Vesicle Lumen Acidification Nicotinamide Nucleotide Metabolic Process Carbohydrate Catabolic Process Secretory Granule Lumen Ficolin-1-rich Granule Lumen Nucleoside Phosphate Catabolic Process Fc-epsilon Receptor Signaling Pathway ATP Hydrolysis Activity Regulation Of Autophagy Low-density Lipoprotein Particle Receptor Binding Monoatomic Cation Transport Intracellular Monoatomic Cation Homeostasis Intracellular Monoatomic Ion Homeostasis ATP Metabolic Process Hexose Metabolic Process Organophosphate Catabolic Process Clathrin-coated Vesicle Membrane Cytosol Monosaccharide Metabolic Process Vacuolar Acidification
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