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ATP6V0E1

Name ATPase H+ transporting V0 subunit e1
Structure PDB 6WLW
Interactors 19 interactors: APOD ATP6V1E1 CDIPT COL8A2 CXCL16 EMP1 GPR25 KIR2DL3 MAL2 MS4A13 MS4A4A NAT8 OPRM1 PLN SYT15 SYT15B TMEM218 TMEM254 YIPF6
GO Annotations Cellular Component
  • Lysosomal Membrane
  • Endosome Membrane
  • Membrane
  • Phagocytic Vesicle Membrane
  • Proton-transporting V-type ATPase Complex
  • Proton-transporting V-type ATPase, V0 Domain
Molecular Function
  • Protein Binding
  • ATPase-coupled Ion Transmembrane Transporter Activity
  • Proton-transporting ATPase Activity, Rotational Mechanism
Biological Process
  • Monoatomic Ion Transport
  • Vacuolar Acidification
  • Regulation Of Macroautophagy
  • Transmembrane Transport
  • Proton Transmembrane Transport
Pathways
  • ROS and RNS production in phagocytes
  • Insulin receptor recycling
  • Transferrin endocytosis and recycling
  • Amino acids regulate mTORC1
  • Ion channel transport
  • Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy
Drugs
  • Tiludronic acid
GWAS
  • Body mass index ( 27455349 )
  • PR interval ( 32439900 )
Entrez ID 8992
HPRD ID 04894
Ensembl ID ENSG00000113732
Uniprot IDs O15342
PDB IDs 6WLW 6WM2 6WM3 6WM4 7U4T 7UNF

© Madhavi K. Ganapathiraju 2012-2026