SEC16B and SEC13

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		SEC16B	SEC13
Gene Name		SEC16 homolog B (S. cerevisiae)	SEC13 homolog (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Kinetochore Nuclear Envelope Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Nuclear Pore Outer Ring Extracellular Vesicular Exosome
	Molecular Function		Protein Binding
	Biological Process	Endoplasmic Reticulum Organization Peroxisome Organization Positive Regulation Of Gene Expression Protein Transport Peroxisome Fission COPII Vesicle Coating Positive Regulation Of Protein Exit From Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum	Mitotic Cell Cycle Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Protein N-linked Glycosylation Via Asparagine Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-translational Protein Modification Cellular Protein Metabolic Process COPII Vesicle Coating MRNA Transport Membrane Organization
Pathways			Mitotic Prometaphase Diseases of glycosylation Separation of Sister Chromatids Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Transport to the Golgi and subsequent modification Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Mitotic Anaphase Antigen Presentation: Folding, assembly and peptide loading of class I MHC M Phase Defective MOGS causes MOGS-CDG (CDG-2b) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 MHC class II antigen presentation Class I MHC mediated antigen processing & presentation COPII (Coat Protein 2) Mediated Vesicle Transport ER to Golgi Transport Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Cell Cycle, Mitotic Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Resolution of Sister Chromatid Cohesion Defective ALG12 causes ALG12-CDG (CDG-1g) Mitotic Metaphase and Anaphase Diseases associated with N-glycosylation of proteins Adaptive Immune System
Drugs
Diseases
GWAS		Body mass index ( 22344221 23563607 19079260 23669352 20935630 23583978) Menarche (age at onset) ( 21102462) Obesity ( 23563607) Schizophrenia ( 23894747) Weight ( 19079260)
Protein-Protein Interactions		1 interactors: SEC13	8 interactors: CLDN12 EGFR NUP98 RAB11A SEC16B SEC31A TRAF5 WDR44
Entrez ID		89866	6396
HPRD ID		11491	02538
Ensembl ID		ENSG00000120341	ENSG00000157020
Uniprot IDs		Q96JE7	A8MWR8 B4DXJ1 P55735
PDB IDs			3BG0 3BG1
Enriched GO Terms of Interacting Partners?		COPII Vesicle Coating COPII-coated Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Vesicle Targeting Localization Within Membrane Membrane Budding Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II ER To Golgi Vesicle-mediated Transport Protein N-linked Glycosylation Via Asparagine Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Protein N-linked Glycosylation MRNA Transport RNA Transport RNA Localization Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Post-translational Protein Modification Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Antigen Processing And Presentation Of Peptide Antigen Golgi Vesicle Transport Antigen Processing And Presentation Establishment Of Organelle Localization Macromolecule Glycosylation Protein Glycosylation Glycosylation Glycoprotein Biosynthetic Process Organelle Localization Glycoprotein Metabolic Process	Membrane Organization COPII Vesicle Coating COPII-coated Vesicle Budding Establishment Of Protein Localization Establishment Of Vesicle Localization Vesicle Localization Cytoplasmic Transport Vesicle Targeting, To, From Or Within Golgi Vesicle Targeting Localization Within Membrane Cellular Component Assembly Protein Localization Establishment Of Organelle Localization Protein Complex Assembly Organelle Localization Cellular Localization Endomembrane System Organization Membrane Budding Alkanesulfonate Metabolic Process Regulation Of Multivesicular Body Size Multivesicular Body Assembly Cellular Protein Localization Protein Localization To Organelle ER To Golgi Vesicle-mediated Transport Protein Transport Response To Calcium Ion Intracellular Transport Protein Import Into Nucleus, Docking Multivesicular Body Organization Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Regulation Of Protein Transport Regulation Of Establishment Of Protein Localization Mitotic Cell Cycle Process Regulation Of Endosome Size Positive Regulation Of Intracellular Protein Transport Mitotic Cell Cycle Activation Of Phospholipase A2 Activity Exosomal Secretion Regulation Of Protein Localization Positive Regulation Of Phospholipase A2 Activity Positive Regulation Of Protein Exit From Endoplasmic Reticulum Establishment Of Localization In Cell Vesicle Organization Response To Cobalamin Response To UV-A Regulation Of Protein Exit From Endoplasmic Reticulum Response To Hydroxyisoflavone Nuclear Pore Complex Assembly Establishment Of Protein Localization To Membrane
Tagcloud ?		abc adulthood aga auckland bdnf birthweight born collaborative concept contribution environmental ethnic evident genetics gestational hypertension kcnj11 maternal mother obesity pfkp polymorphisms postnatal prevalent pter sga snps stature undertook	antagonized borne brefeldin collectively copii delivering depletion enterocytes imposed inlc junctions listeria monocytogenes motile motility otherwise perturbed precipitation protrusion protrusions relieves sar1 scaffolding sec31a spread tension termed tuba uses
Tagcloud (Difference) ?		abc adulthood aga auckland bdnf birthweight born collaborative concept contribution environmental ethnic evident genetics gestational hypertension kcnj11 maternal mother obesity pfkp polymorphisms postnatal prevalent pter sga snps stature undertook	antagonized borne brefeldin collectively copii delivering depletion enterocytes imposed inlc junctions listeria monocytogenes motile motility otherwise perturbed precipitation protrusion protrusions relieves sar1 scaffolding sec31a spread tension termed tuba uses
Tagcloud (Intersection) ?