KLHL6 and PPP1R1B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KLHL6	PPP1R1B
Gene Name		kelch-like family member 6	protein phosphatase 1, regulatory (inhibitor) subunit 1B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm Cytosol Neuronal Cell Body
	Molecular Function		Protein Kinase Inhibitor Activity Protein Phosphatase Inhibitor Activity Protein Serine/threonine Phosphatase Inhibitor Activity Protein Phosphatase Type 1 Regulator Activity D1 Dopamine Receptor Binding D2 Dopamine Receptor Binding D3 Dopamine Receptor Binding D4 Dopamine Receptor Binding D5 Dopamine Receptor Binding
	Biological Process	Germinal Center Formation B Cell Receptor Signaling Pathway	Response To Amphetamine Transcription, DNA-templated Negative Regulation Of Protein Kinase Activity Signal Transduction Negative Regulation Of Female Receptivity Visual Learning Intracellular Signal Transduction Negative Regulation Of Catalytic Activity Regulation Of Catalytic Activity
Pathways			Signaling by GPCR Opioid Signalling DARPP-32 events
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: PPP1R1B UBC	9 interactors: CDK5 CSNK2A1 CSNK2A2 DLGAP4 KLHL6 PPP1CA PRKACA ROBO2 TFCP2
Entrez ID		89857	84152
HPRD ID		10035	05097
Ensembl ID		ENSG00000172578	ENSG00000131771
Uniprot IDs		Q8WZ60	B3KVQ9 Q9UD71
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transferase Activity Negative Regulation Of Female Receptivity Viral Protein Processing Regulation Of Protein Kinase Activity Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Female Receptivity Female Mating Behavior Negative Regulation Of Protein Metabolic Process Notch Receptor Processing Virion Assembly Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Protein Phosphorylation Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Response To Abiotic Stimulus Glycogen Biosynthetic Process Intracellular Transport Of Virus Mating Behavior Response To Amphetamine Regulation Of Phosphorylation Cellular Polysaccharide Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Polysaccharide Biosynthetic Process Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Negative Regulation Of ERBB Signaling Pathway Response To Amine Mating Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Toll-like Receptor 2 Signaling Pathway Signal Transduction Involved In DNA Damage Checkpoint Toll-like Receptor 9 Signaling Pathway Signal Transduction Involved In Cell Cycle Checkpoint Glycogen Metabolic Process Visual Learning TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity	Chemotaxis Rhythmic Process Axon Guidance Regulation Of Protein Processing Apoptotic Process Response To External Stimulus Programmed Cell Death Cell Death Death Regulation Of Cell Cycle Process Triglyceride Catabolic Process Axonogenesis Axon Development Acylglycerol Catabolic Process Cell Morphogenesis Involved In Neuron Differentiation Locomotion Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Export From Nucleus Neuron Projection Morphogenesis Cell Cycle Regulation Of Proteolysis Anatomical Structure Morphogenesis Signaling Cell Communication Cell Morphogenesis Involved In Differentiation Mitotic Spindle Checkpoint Movement Of Cell Or Subcellular Component Negative Regulation Of Chromosome Segregation Peptidyl-threonine Phosphorylation Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Negative Regulation Of Cellular Protein Metabolic Process Neuron Projection Development Regulation Of Mitotic Metaphase/anaphase Transition Cell Projection Morphogenesis Cell Part Morphogenesis Negative Regulation Of Protein Metabolic Process Response To Light Stimulus Regulation Of Cell Cycle Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Development Negative Regulation Of Proteolysis Negative Regulation Of Proteasomal Protein Catabolic Process Neuron Development Negative Regulation Of Protein Processing Regulation Of Protein Catabolic Process Regulation Of Cellular Component Organization Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Dense Core Granule Biogenesis
Tagcloud ?		accounting atm bioinformatics birc3 concordance confirmation conservative cutoff discordant eventually haloplex hiseq ighv ighv3 lymphocytic myd88 next notch1 pot1 precision recurrently repeating reproducible sanger sequencing sf3b1 stand unmutated xpo1	17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis ikzf3 immumohistochemical implied per1 perld1 q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Difference) ?		accounting atm bioinformatics birc3 concordance confirmation conservative cutoff discordant eventually haloplex hiseq ighv ighv3 lymphocytic myd88 next notch1 pot1 precision recurrently repeating reproducible sanger sequencing sf3b1 stand unmutated xpo1	17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis ikzf3 immumohistochemical implied per1 perld1 q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Intersection) ?