KLHL6

Description		kelch like family member 6
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Germinal Center Formation Response To Bacterium Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process B Cell Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Youthful appearance (self-reported) ( 32339537)
Interacting Genes		8 interacting genes: BYSL CDK2 CRY2 CUL3 FH PPP1R1B SBDS TMPO
Entrez ID		89857
HPRD ID		10035
Ensembl ID		ENSG00000172578
Uniprot IDs		Q8WZ60
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Cytoplasm Macromolecule Metabolic Process RNA Metabolic Process Nucleus DNA-templated Transcription Cell Cycle G1/S Phase Transition Cyclin Binding G1/S Transition Of Mitotic Cell Cycle Y Chromosome Positive Regulation Of Heterochromatin Formation Cyclin A1-CDK2 Complex Cyclin E2-CDK2 Complex Positive Regulation Of DNA-templated DNA Replication Initiation Photoreactive Repair Blue Light Signaling Pathway DNA (6-4) Photolyase Activity Deoxyribodipyrimidine Photo-lyase Activity Blue Light Photoreceptor Activity Protein Phosphatase Inhibitor Activity Fumarate Metabolic Process Fumarate Hydratase Activity Trophectodermal Cellular Morphogenesis Liver Morphogenesis Ribosome Biogenesis Positive Regulation Of Chromatin Organization DNA Repair Cyclin-dependent Protein Kinase Activity Cyclin A2-CDK2 Complex Cyclin E1-CDK2 Complex Cry-Per Complex Regulation Protein Catabolic Process At Postsynapse Cytosol X Chromosome Negative Regulation Of Glucocorticoid Secretion POZ Domain Binding Negative Regulation Of Female Receptivity Mitotic Cell Cycle Phase Transition Regulation Of Sodium-dependent Phosphate Transport Regulation Of Arginine Metabolic Process Polar Microtubule Spindle Pole Cytosolic Ribosome Assembly Cell Cycle Phase Transition Response To Insulin Ribonucleoprotein Complex Biogenesis Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Histone Kinase Activity Response To Blue Light
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