NAV2 and ING4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NAV2	ING4
Gene Name		neuron navigator 2	inhibitor of growth family, member 4
Image
Gene Ontology Annotations	Cellular Component	Interstitial Matrix Nucleoplasm	Histone Acetyltransferase Complex Nucleus Nucleoplasm
	Molecular Function	Helicase Activity ATP Binding Heparin Binding	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Methylated Histone Binding
	Biological Process	Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Sensory Perception Of Sound Sensory Perception Of Smell Locomotory Behavior Metabolic Process Optic Nerve Development Glossopharyngeal Nerve Development Vagus Nerve Development	DNA Replication Chromatin Organization Protein Acetylation Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Cell Cycle Arrest Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Growth
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		10 interactors: ADAT2 APC CFAP58 ING4 ING5 MORF4L1 PIAS2 RBM15 RBM15B RRAS	17 interactors: CDC34 EGLN1 EP300 HIST1H3A HIST3H3 HNRNPD HOXB9 JADE1 JADE2 KAT7 MSX1 MYC NAV2 RELA SUV39H1 TLX3 TP53
Entrez ID		89797	51147
HPRD ID		07385	09774
Ensembl ID		ENSG00000166833	ENSG00000111653
Uniprot IDs		A7E2D6 Q8IVL1	Q9UNL4
PDB IDs		2YRN	2K1J 2M1R 2PNX 2VNF 4AFL
Enriched GO Terms of Interacting Partners?		Peptidyl-lysine Modification Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Histone H3 Acetylation Histone H4 Acetylation Peptidyl-amino Acid Modification Histone Modification Chromosome Organization TRNA Wobble Adenosine To Inosine Editing Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Regulation Of Osteoblast Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Chromatin Modification Cell Cycle Arrest Positive Regulation Of Cell Death Regulation Of Growth Negative Regulation Of Odontogenesis Negative Regulation Of Cell Proliferation Positive Regulation Of Transcription Of Notch Receptor Target Immune System Development Regulation Of Myeloid Cell Differentiation Chromatin Organization Regulation Of RNA Metabolic Process Regulation Of Ossification Nucleobase-containing Compound Metabolic Process Metaphase/anaphase Transition Of Mitotic Cell Cycle Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Cellular Response To DNA Damage Stimulus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of Growth Histone H4-K12 Acetylation Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Microtubule Polymerization DNA Replication Positive Regulation Of Pseudopodium Assembly DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Histone H4-K5 Acetylation Histone H4-K8 Acetylation Negative Regulation Of Androgen Receptor Signaling Pathway	Chromosome Organization Chromatin Organization Histone H4-K12 Acetylation Histone H4 Acetylation Heterocycle Metabolic Process Histone H4-K5 Acetylation Histone H4-K8 Acetylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Hypoxia Transcription, DNA-templated Cellular Response To Decreased Oxygen Levels Peptidyl-lysine Modification Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Cellular Response To Oxygen Levels Histone Acetylation Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Cellular Nitrogen Compound Metabolic Process Protein Acetylation Chromatin Modification Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Histone H3 Acetylation Cellular Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Macromolecule Biosynthetic Process Histone Modification Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Cellular Response To Nicotine Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Anterior/posterior Pattern Specification
Tagcloud ?		amplifications analysing apc arid1a considerably copy epsilon excluding exome fam123b hypermethylation hypermutated igf2 integrative messenger microrna microsatellite mismatch mlh1 pik3ca pole quarter quarters rectum smad4 sox9 targetable tcf7l1 translocations	aad adenovirus adopted apparently arrested bax bcl blot caspase cleaved cne differential efect g2 measure mtt nasopharyngeal obviously overexpressed p21 pe probable regulating rgd rt survivin synergies vector western
Tagcloud (Difference) ?		amplifications analysing apc arid1a considerably copy epsilon excluding exome fam123b hypermethylation hypermutated igf2 integrative messenger microrna microsatellite mismatch mlh1 pik3ca pole quarter quarters rectum smad4 sox9 targetable tcf7l1 translocations	aad adenovirus adopted apparently arrested bax bcl blot caspase cleaved cne differential efect g2 measure mtt nasopharyngeal obviously overexpressed p21 pe probable regulating rgd rt survivin synergies vector western
Tagcloud (Intersection) ?