NAV1 and RSRC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NAV1	RSRC2
Description		neuron navigator 1	arginine and serine rich coiled-coil 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Microtubule Microtubule Cytoskeleton Axon Initial Segment
	Molecular Function	Protein Binding	RNA Binding Protein Binding
	Biological Process	Microtubule Bundle Formation Neuron Migration Nervous System Development Neurogenesis Cell Differentiation
Pathways
Drugs
Diseases
GWAS		BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 29273807 25673413 26961502 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Calcific aortic valve stenosis ( 32141789) Celiac disease ( 23936387) Diastolic blood pressure ( 30578418) Femur bone mineral density x serum urate levels interaction ( 34046847) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Neurociticism ( 29500382) Obesity-related traits ( 23251661) Optic disc size ( 31809533) Pulse pressure ( 27841878 30578418) Sepsis (hospital admission) ( 32592749) Sleep duration (short sleep) ( 30846698) Waist circumference ( 25673412)	Hip circumference adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		10 interacting genes: APC APP DDIT4L GCC1 KIFAP3 KRT31 MAPRE1 PRIMPOL RSRC2 TBC1D4	21 interacting genes: AKAP9 APP CMTM5 CTAG1A CTAG1B GOLGA2 KASH5 NAV1 OGT PFDN5 PNMA1 RINT1 SAMD4B SRPK1 SRPK2 TRIM23 TRIM54 UBQLN1 UBQLN2 UBQLN4 UPF2
Entrez ID		89796	65117
HPRD ID		10113	13342
Ensembl ID		ENSG00000134369	ENSG00000111011
Uniprot IDs		A0A8I5KSE4 Q8NEY1	Q7L4I2
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule Plus-end Binding Golgi Apparatus Protein Serine/threonine Kinase Binding Cytoplasmic Microtubule Microtubule Cytoskeleton Negative Regulation Of Microtubule Polymerization Or Depolymerization Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Localization To Astral Microtubule Positive Regulation Of Calcium-dependent Cell-cell Adhesion Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Supramolecular Fiber Organization Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Axo-dendritic Transport Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Protein Localization To Mitotic Spindle Mitotic Spindle Astral Microtubule End Cortical Microtubule Cytoskeleton Protein Localization To Spindle Microtubule Kinesin II Complex	Cytoplasm Positive Regulation Of Response To Endoplasmic Reticulum Stress Polyubiquitin Modification-dependent Protein Binding Response To Stress Regulation Of Proteolysis Regulation Of Protein Catabolic Process Regulation Of Autophagy Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Identical Protein Binding Autophagosome Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Amyloid Fibril Formation Positive Regulation Of ERAD Pathway Regulation Of Protein Metabolic Process Macromolecule Metabolic Process TRNA Threonylcarbamoyladenosine Metabolic Process Microtubule-based Process Autophagy Regulation Of ERAD Pathway Microtubule Nucleation Positive Regulation Of Viral Genome Replication Amyloid-beta Complex Innate Immune Response Growth Cone Lamellipodium Protein-containing Complex Organization Regulation Of Response To Calcium Ion Amylin Binding Cellular Component Assembly Regulation Of Supramolecular Fiber Organization Positive Regulation Of Toll Signaling Pathway Defense Response RNA Polymerase III Assembly RNA Polymerase I Assembly Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Store-operated Calcium Channel Activity Negative Regulation Of Cellular Component Organization Organelle Assembly Cis-Golgi Network Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Regulation Of Macroautophagy Defense Response To Symbiont Regulation Of Glycolytic Process Defense Response To Other Organism Protein-containing Complex Nucleic Acid Metabolic Process Microtubule Cytoskeleton Organization Positive Regulation Of Protein Catabolic Process
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