NAV1 and MAPRE1

Number of citations of the paper that reports this interaction (PMID 25065758)
0

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		NAV1	MAPRE1
Gene Name		neuron navigator 1	microtubule-associated protein, RP/EB family, member 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule	Cytoplasm Golgi Apparatus Centrosome Spindle Cytosol Microtubule Cytoplasmic Microtubule Cortical Microtubule Cytoskeleton Cell Projection Membrane Microtubule Plus-end
	Molecular Function		Protein Binding Protein C-terminus Binding Poly(A) RNA Binding Microtubule Plus-end Binding
	Biological Process	Microtubule Bundle Formation Neuron Migration	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Cell Proliferation Negative Regulation Of Microtubule Polymerization Protein Localization To Microtubule Cell Division Positive Regulation Of Microtubule Plus-end Binding
Pathways			Mitotic Prometaphase Organelle biogenesis and maintenance Separation of Sister Chromatids Assembly of the primary cilium G2/M Transition Mitotic Anaphase Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane M Phase Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Resolution of Sister Chromatid Cohesion Loss of Nlp from mitotic centrosomes Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		6 interactors: APC APP GCC1 KRT31 MAPRE1 TBC1D4	40 interactors: ABCB1 APC APC2 APP AURKB BCL3 CDK5RAP2 CLASP1 CLASP2 CLIP1 COPS5 COPS8 CSN3 CYLD DCTN1 HSPA1A IKBKG KAT2B KAT5 KIF2C LMO2 LRP1 MACF1 MAPRE2 MAPRE3 NAV1 NUPR1 PDE4DIP PIK3R4 POLE2 PQBP1 PSMA1 SPDYE2 STK11 TERF1 TRAF2 TRIO TROAP TUBA1A TUBB
Entrez ID		89796	22919
HPRD ID		10113	04379
Ensembl ID		ENSG00000134369	ENSG00000101367
Uniprot IDs		Q8NEY1	B4DM33 Q15691
PDB IDs			1PA7 1TXQ 1UEG 1VKA 1WU9 1YIB 1YIG 2HKQ 2HL3 2HL5 2QJZ 2R8U 3GJO 3TQ7
Enriched GO Terms of Interacting Partners?		Regulation Of Microtubule Polymerization Negative Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule Polymerization Or Depolymerization Synaptic Growth At Neuromuscular Junction Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Regulation Of Microtubule Cytoskeleton Organization Regulation Of Protein Binding Negative Regulation Of Cytoskeleton Organization Regulation Of Microtubule-based Process Collateral Sprouting In Absence Of Injury Positive Regulation Of Microtubule Plus-end Binding Negative Regulation Of Odontogenesis Regulation Of Organelle Organization Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Metaphase/anaphase Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Regulation Of Binding Cell Cycle Phase Transition Epidermis Development Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Protein Localization To Microtubule Negative Regulation Of Vesicle Fusion Neuron Remodeling Mitotic Nuclear Division Regulation Of Protein Complex Assembly Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Microtubule Polymerization Negative Regulation Of Proteolysis Positive Regulation Of Pseudopodium Assembly Negative Regulation Of Protein Processing Negative Regulation Of Microtubule Polymerization Vesicle-mediated Transport Regulation Of Protein Processing Regulation Of Mitotic Cell Cycle Cell Division Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Cellular Copper Ion Homeostasis Regulation Of Attachment Of Spindle Microtubules To Kinetochore Protein Localization To Cytoskeleton Copper Ion Homeostasis Suckling Behavior Protein Targeting To Golgi Regulation Of Cell Cycle Process Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi	Cell Cycle Process Mitotic Cell Cycle Process Cell Cycle Mitotic Cell Cycle Mitotic Nuclear Division Regulation Of Microtubule-based Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Division Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Cycle G2/M Transition Of Mitotic Cell Cycle Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Cell Cycle Microtubule Cytoskeleton Organization Microtubule-based Process Response To Stimulus Organelle Organization Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Protein Complex Assembly Regulation Of Cytoskeleton Organization Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Microtubule Depolymerization Regulation Of Chromosome Segregation Cullin Deneddylation Cellular Localization Regulation Of Wnt Signaling Pathway Establishment Or Maintenance Of Cell Polarity Response To Radiation Protein Deneddylation Negative Regulation Of Microtubule Polymerization Or Depolymerization Cellular Component Assembly Spindle Checkpoint Positive Regulation Of Microtubule Polymerization Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Component Organization Microtubule Bundle Formation Response To Light Stimulus Cellular Protein Complex Assembly Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Positive Regulation Of Metabolic Process Regulation Of Apoptotic Process Cellular Response To Stimulus Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Positive Regulation Of Transferase Activity
Tagcloud ?		14d 7d actived bilatral contralateral drg dropped fluorocitrate fluorocitric glial hind hindpaws hyperalgesia hypersensitivity intrathecal ipsilateral l5 ligated mip mirror paw paws sectioned sham sides snl threshold weighing withdrawal	akap450 akap9 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant
Tagcloud (Difference) ?		14d 7d actived bilatral contralateral drg dropped fluorocitrate fluorocitric glial hind hindpaws hyperalgesia hypersensitivity intrathecal ipsilateral l5 ligated mip mirror paw paws sectioned sham sides snl threshold weighing withdrawal	akap450 akap9 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant
Tagcloud (Intersection) ?