MCM3AP and NUDT5

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MCM3AP	NUDT5
Description		minichromosome maintenance complex component 3 associated protein	nudix hydrolase 5
Image
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Chromosome Cytoplasm Cytosol Nuclear Membrane Protein-containing Complex Nuclear Pore Nuclear Basket Transcription Export Complex 2	Nucleus Cytosol Extracellular Exosome
	Molecular Function	Nucleic Acid Binding Chromatin Binding Histone Acetyltransferase Activity Protein Binding Histone H3 Acetyltransferase Activity Transferase Activity Acyltransferase Activity Histone Binding	Magnesium Ion Binding RNA Binding Protein Binding Transferase Activity Nucleotidyltransferase Activity Hydrolase Activity Nucleoside Diphosphate Phosphatase Activity ADP-sugar Diphosphatase Activity SnoRNA Binding Identical Protein Binding Protein Homodimerization Activity 8-oxo-dGDP Phosphatase Activity Metal Ion Binding ADP-ribose Diphosphatase Activity 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] Hydrolase Activity
	Biological Process	Immune System Process MRNA Export From Nucleus Protein Transport Somatic Hypermutation Of Immunoglobulin Genes Poly(A)+ MRNA Export From Nucleus Nucleosome Organization MRNA Transport	Nucleobase-containing Compound Metabolic Process Chromatin Remodeling Nucleoside Phosphate Metabolic Process Nucleotide Metabolic Process Ribonucleoside Diphosphate Catabolic Process D-ribose Catabolic Process Ribose Phosphate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process ATP Generation From Poly-ADP-D-ribose
Pathways			Phosphate bond hydrolysis by NUDT proteins
Drugs
Diseases
GWAS		Monocyte percentage of white cells ( 32888494) Periodontitis ( 30218097) Testicular germ cell tumor ( 23666240 25877299 28604728)	Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)
Interacting Genes		19 interacting genes: APC CDC25A CDC42 CDC73 CLSTN1 CRMP1 ENY2 EP300 FAM118B MCM3 NUDT5 POLR2G RAC1 SMAD3 SMAD9 SUV39H2 TAF1D TMEM216 TSC22D1	5 interacting genes: COX5B GORASP2 MAPK6 MCM3AP NUDT3
Entrez ID		8888	11164
HPRD ID		04483	14851
Ensembl ID		ENSG00000160294	ENSG00000165609
Uniprot IDs		O60318	Q9UKK9
PDB IDs		4DHX	2DSB 2DSC 2DSD 3AC9 3ACA 3BM4 3L85 5NQR 5NWH 5QJ4 5QJ5 5QJ6 5QJ7 5QJ8 5QJ9 5QJA 5QJB 5QJC 5QJD 5QJE 5QJF 5QJG 5QJH 5QJI 5QJJ 5QJK 5QJL 5QJM 5QJN 5QJO 5QJP 5QJQ 5QJR 5QJS 5QJT 5QJU 5QJV 5QJW 5QJX 5QJY 5QJZ 5QK0 5QK1 5QK2 5QK3 5QK4 5QK5 5QK6 5QK7 5QK8 5QK9 5QKA 5QKB 5QTL 5QTM 5QTN 5QTO 5QTP 5QTQ 5QTR 5QTS 6GRU 8PTT 8RDZ 8RIY
Enriched GO Terms of Interacting Partners?		Cell-cell Junction Organization Leading Edge Membrane Wnt Signaling Pathway Nucleus Thioesterase Binding G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Actin Filament Bundle Assembly SMAD Protein Complex Heteromeric SMAD Protein Complex Positive Regulation Of Pseudopodium Assembly Protein Kinase Binding I-SMAD Binding Beta-catenin Binding Positive Regulation Of Cellular Component Biogenesis Regulation Of Stress Fiber Assembly Regulation Of Cell Junction Assembly Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Cell Junction Assembly GTP-dependent Protein Binding Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Regulation Of Attachment Of Spindle Microtubules To Kinetochore Regulation Of Synapse Organization Regulation Of Primary Metabolic Process Positive Regulation Of Cell-substrate Adhesion SMAD Protein Signal Transduction Positive Regulation Of Lamellipodium Assembly Regulation Of Postsynapse Organization Phagocytosis, Engulfment Positive Regulation Of Focal Adhesion Assembly Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Projection Organization Regulation Of Cell Projection Organization Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Lamellipodium Organization Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Cellular Component Organization Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Cellular Component Organization Nucleoplasm Cell Surface Receptor Signaling Pathway Regulation Of Supramolecular Fiber Organization Cytosol Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Supramolecular Fiber Organization Regulation Of Cell Growth Regulation Of Lamellipodium Assembly	Regulation Of Cellular Response To X-ray Negative Regulation Of Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Involved In Ureteric Bud Formation Type IV Hypersensitivity Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Ureteric Bud Formation Negative Regulation Of Cell Proliferation Involved In Mesonephros Development Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity Diphosphoinositol Polyphosphate Catabolic Process Pro-T Cell Differentiation Parathyroid Hormone Secretion Septin Cytoskeleton 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] Diphosphatase Activity Diphosphoinositol Polyphosphate Metabolic Process Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity Bis(5'-adenosyl)-hexaphosphatase Activity Diadenosine Hexaphosphate Catabolic Process Inositol Phosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process Diphosphoinositol-polyphosphate Diphosphatase Activity Endopolyphosphatase Activity Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity Nephric Duct Formation Regulation Of Thyroid Hormone Generation Positive Regulation Of Ureteric Bud Formation Ureter Maturation Positive Regulation Of Thyroid Hormone Generation Mast Cell Differentiation Bis(5'-adenosyl)-pentaphosphatase Activity Diadenosine Polyphosphate Catabolic Process Ureteric Bud Formation Interleukin-2 Receptor Binding Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Cell Proliferation Involved In Kidney Development Immune System Development Transcription Export Complex 2 Parathyroid Gland Development Mesonephric Tubule Formation Ureter Morphogenesis Otic Vesicle Development Nephric Duct Morphogenesis Norepinephrine Biosynthetic Process Histone H3 Acetyltransferase Activity T-helper 2 Cell Differentiation Positive Regulation Of T-helper 2 Cell Cytokine Production Positive Regulation Of Epithelial Tube Formation Cellular Response To Interferon-alpha 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] Hydrolase Activity Cytochrome-c Oxidase Activity Positive Regulation Of Transcription Regulatory Region DNA Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?