MCM3AP and TMEM216

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MCM3AP	TMEM216
Gene Name		minichromosome maintenance complex component 3 associated protein	transmembrane protein 216
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Nuclear Membrane	Cytosol Cytoskeleton Cilium Integral Component Of Membrane TCTN-B9D Complex
	Molecular Function	DNA Binding Transferase Activity, Transferring Acyl Groups
	Biological Process	Immune System Process DNA Replication Protein Import Into Nucleus MRNA Transport	Organelle Organization Cilium Assembly Cilium Morphogenesis
Pathways			Organelle biogenesis and maintenance Assembly of the primary cilium Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		19 interactors: APC CDC25A CDC42 CDC73 CLSTN1 CRMP1 ENY2 EP300 FAM118B MCM3 NUDT5 POLR2G RAC1 SMAD3 SMAD9 SUV39H2 TAF1D TMEM216 TSC22D1	1 interactors: MCM3AP
Entrez ID		8888	51259
HPRD ID		04483	14439
Ensembl ID		ENSG00000160294	ENSG00000187049
Uniprot IDs		O60318	Q9P0N5
PDB IDs		4DHX
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Protein Stability Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Cell-cell Junction Organization Posttranscriptional Regulation Of Gene Expression RNA Biosynthetic Process Anatomical Structure Morphogenesis Organelle Organization Regulation Of Nitrogen Compound Metabolic Process Cell Cycle DNA-templated Transcription, Elongation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Pseudopodium Assembly Regulation Of Cell Cycle Wnt Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of MRNA 3'-end Processing Response To Hypoxia Positive Regulation Of Cell Death Chromosome Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of MRNA 3'-end Processing Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Positive Regulation Of Cell-substrate Adhesion Regulation Of Cell Projection Assembly Epithelium Development Response To Abiotic Stimulus Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Adherens Junction Organization Positive Regulation Of Cell Adhesion Tissue Development Biosynthetic Process Histone Modification Stem Cell Maintenance Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Wnt Signaling Pathway Cell Development	MRNA Transport Protein Import Into Nucleus Nuclear Import RNA Transport RNA Localization Protein Import Protein Localization To Nucleus Nucleocytoplasmic Transport Nuclear Transport DNA Replication Establishment Of Protein Localization To Organelle
Tagcloud ?		adenomatous arhgap causative cntn6 cnv cnvs ctnnb1 etiologically filtered focad german germline hsph1 kiaa1797 kif26b mining mutyh ngs nonrecurrent polyposis predispose predisposition prioritized silico stringent truncating uncover unexplained ybey
Tagcloud (Difference) ?		adenomatous arhgap causative cntn6 cnv cnvs ctnnb1 etiologically filtered focad german germline hsph1 kiaa1797 kif26b mining mutyh ngs nonrecurrent polyposis predispose predisposition prioritized silico stringent truncating uncover unexplained ybey
Tagcloud (Intersection) ?