NUDT5 and MCM3AP

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NUDT5	MCM3AP
Gene Name		nudix (nucleoside diphosphate linked moiety X)-type motif 5	minichromosome maintenance complex component 3 associated protein
Image
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Cytosol Extracellular Vesicular Exosome	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Nuclear Membrane
	Molecular Function	Magnesium Ion Binding Nucleoside-diphosphatase Activity ADP-sugar Diphosphatase Activity SnoRNA Binding ADP-ribose Diphosphatase Activity M7G(5')pppN Diphosphatase Activity	DNA Binding Transferase Activity, Transferring Acyl Groups
	Biological Process	Nucleotide Metabolic Process Ribonucleoside Diphosphate Catabolic Process D-ribose Catabolic Process Nucleobase-containing Small Molecule Catabolic Process Small Molecule Metabolic Process Nucleobase-containing Small Molecule Metabolic Process	Immune System Process DNA Replication Protein Import Into Nucleus MRNA Transport
Pathways		Phosphate bond hydrolysis by NUDT proteins Metabolism of nucleotides
Drugs
Diseases
GWAS			Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		3 interactors: MAPK6 MCM3AP NUDT3	19 interactors: APC CDC25A CDC42 CDC73 CLSTN1 CRMP1 ENY2 EP300 FAM118B MCM3 NUDT5 POLR2G RAC1 SMAD3 SMAD9 SUV39H2 TAF1D TMEM216 TSC22D1
Entrez ID		11164	8888
HPRD ID		14851	04483
Ensembl ID		ENSG00000165609	ENSG00000160294
Uniprot IDs		Q9UKK9	O60318
PDB IDs		2DSB 2DSC 2DSD 3AC9 3ACA 3BM4 3L85	4DHX
Enriched GO Terms of Interacting Partners?		Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process	Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Protein Stability Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Cell-cell Junction Organization Posttranscriptional Regulation Of Gene Expression RNA Biosynthetic Process Anatomical Structure Morphogenesis Organelle Organization Regulation Of Nitrogen Compound Metabolic Process Cell Cycle DNA-templated Transcription, Elongation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Pseudopodium Assembly Regulation Of Cell Cycle Wnt Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of MRNA 3'-end Processing Response To Hypoxia Positive Regulation Of Cell Death Chromosome Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of MRNA 3'-end Processing Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Positive Regulation Of Cell-substrate Adhesion Regulation Of Cell Projection Assembly Epithelium Development Response To Abiotic Stimulus Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Adherens Junction Organization Positive Regulation Of Cell Adhesion Tissue Development Biosynthetic Process Histone Modification Stem Cell Maintenance Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Wnt Signaling Pathway Cell Development
Tagcloud ?			adenomatous arhgap causative cntn6 cnv cnvs ctnnb1 etiologically filtered focad german germline hsph1 kiaa1797 kif26b mining mutyh ngs nonrecurrent polyposis predispose predisposition prioritized silico stringent truncating uncover unexplained ybey
Tagcloud (Difference) ?			adenomatous arhgap causative cntn6 cnv cnvs ctnnb1 etiologically filtered focad german germline hsph1 kiaa1797 kif26b mining mutyh ngs nonrecurrent polyposis predispose predisposition prioritized silico stringent truncating uncover unexplained ybey
Tagcloud (Intersection) ?