SYNJ2 and SYNJ2BP

Number of citations of the paper that reports this interaction (PMID 10357812)
30

Data Source:
HPRD (in vitro, in vivo)

		SYNJ2	SYNJ2BP
Gene Name		synaptojanin 2	synaptojanin 2 binding protein
Image
Gene Ontology Annotations	Cellular Component	Cytosol Membrane	Mitochondrion Cell Surface Integral Component Of Mitochondrial Outer Membrane
	Molecular Function	Nucleotide Binding RNA Binding Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Protein Binding	Protein C-terminus Binding Type II Activin Receptor Binding
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Small Molecule Metabolic Process Phosphatidylinositol Dephosphorylation	Positive Regulation Of Receptor Internalization Negative Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Activin Receptor Signaling Pathway Intracellular Distribution Of Mitochondria Positive Regulation Of Protein Localization To Cell Surface
Pathways		Synthesis of PIPs at the plasma membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS		Cannabis use (initiation) ( 22823124)
Protein-Protein Interactions		7 interactors: GRB2 ITSN1 ITSN2 NCK1 RAC1 SH3GL2 SYNJ2BP	10 interactors: ACTB ACVR2A ACVR2B APP LRP1 LRP2 LRP8 RALBP1 SYNJ2 USHBP1
Entrez ID		8871	55333
HPRD ID		10259	15455
Ensembl ID		ENSG00000078269
Uniprot IDs		B4DG94 O15056	P57105
PDB IDs		1UFW	2ENO 2JIK 2JIN
Enriched GO Terms of Interacting Partners?		Endocytosis Axon Guidance Axonogenesis Positive Regulation Of Signal Transduction Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Neuron Projection Morphogenesis Regulation Of Signal Transduction Vesicle-mediated Transport Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Regulation Of Signaling Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Neuron Development Positive Regulation Of Actin Filament Polymerization Cell Morphogenesis Positive Regulation Of Protein Polymerization Neuron Differentiation Cell Projection Organization Locomotion Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To Growth Factor Stimulus Positive Regulation Of Protein Complex Assembly Response To Growth Factor Regulation Of Actin Filament Polymerization Regulation Of Endocytosis Movement Of Cell Or Subcellular Component Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of T Cell Activation Generation Of Neurons Positive Regulation Of Homotypic Cell-cell Adhesion Neurogenesis Regulation Of Receptor Internalization Positive Regulation Of Cell-cell Adhesion Regulation Of Intracellular Signal Transduction Phagocytosis Synaptic Vesicle Endocytosis Cell Development Fc Receptor Signaling Pathway Response To External Stimulus	Endocytosis Phototransduction, Visible Light Positive Regulation Of Activin Receptor Signaling Pathway Retinoid Metabolic Process Diterpenoid Metabolic Process Detection Of Visible Light Response To Light Stimulus Phototransduction Detection Of Light Stimulus Isoprenoid Metabolic Process Response To External Stimulus Response To Radiation Regulation Of Activin Receptor Signaling Pathway Detection Of Abiotic Stimulus Signal Transduction Lipid Metabolic Process Activin Receptor Signaling Pathway Regulation Of Catalytic Activity Anatomical Structure Morphogenesis Signaling Vesicle-mediated Transport Cell Communication Steroid Metabolic Process Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Brain Development System Development Head Development Mating Gastrulation With Mouth Forming Second Regulation Of Protein Tyrosine Kinase Activity Alcohol Metabolic Process Organ Development Cellular Response To Stimulus Receptor-mediated Endocytosis Artery Development Regulation Of Signaling Cellular Lipid Metabolic Process Central Nervous System Development Cell Surface Receptor Signaling Pathway Multicellular Organismal Development Regulation Of Bone Mineralization Positive Regulation Of Osteoblast Differentiation BMP Signaling Pathway Anatomical Structure Development Ammon Gyrus Development Beta-amyloid Clearance Regulation Of Protein Phosphorylation Transport Blood Coagulation
Tagcloud ?		aberrations abundance amplified block copy druggable encodes endocytic gain gains inositol invadopodia knocking lamellipodia libraries member microrna migration neural phosphatase promoted recycling search shorter similarly synaptojanin synj1 targetable xenografts
Tagcloud (Difference) ?		aberrations abundance amplified block copy druggable encodes endocytic gain gains inositol invadopodia knocking lamellipodia libraries member microrna migration neural phosphatase promoted recycling search shorter similarly synaptojanin synj1 targetable xenografts
Tagcloud (Intersection) ?