SYNJ2

Gene Name		synaptojanin 2
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Gene Ontology Annotations	Cellular Component	Cytosol Membrane
	Molecular Function	Nucleotide Binding RNA Binding Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Protein Binding
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Small Molecule Metabolic Process Phosphatidylinositol Dephosphorylation
Pathways		Synthesis of PIPs at the plasma membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS		Cannabis use (initiation) ( 22823124)
Protein-protein Interactions		7 interactors: GRB2 ITSN1 ITSN2 NCK1 RAC1 SH3GL2 SYNJ2BP
Entrez ID		8871
HPRD ID		10259
Ensembl ID		ENSG00000078269
Uniprot IDs		B4DG94 O15056
PDB IDs		1UFW
Enriched GO Terms of Interacting Partners?		Endocytosis Axon Guidance Axonogenesis Positive Regulation Of Signal Transduction Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Neuron Projection Morphogenesis Regulation Of Signal Transduction Vesicle-mediated Transport Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Regulation Of Signaling Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Neuron Development Positive Regulation Of Actin Filament Polymerization Cell Morphogenesis Positive Regulation Of Protein Polymerization Neuron Differentiation Cell Projection Organization Locomotion Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To Growth Factor Stimulus Positive Regulation Of Protein Complex Assembly Response To Growth Factor Regulation Of Actin Filament Polymerization Regulation Of Endocytosis Movement Of Cell Or Subcellular Component Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of T Cell Activation Generation Of Neurons Positive Regulation Of Homotypic Cell-cell Adhesion Neurogenesis Regulation Of Receptor Internalization Positive Regulation Of Cell-cell Adhesion Regulation Of Intracellular Signal Transduction Phagocytosis Synaptic Vesicle Endocytosis Cell Development Fc Receptor Signaling Pathway Response To External Stimulus
Tagcloud ?		aberrations abundance amplified block copy druggable encodes endocytic gain gains inositol invadopodia knocking lamellipodia libraries member microrna migration neural phosphatase promoted recycling search shorter similarly synaptojanin synj1 targetable xenografts