TMEM11 and BNIP3

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		TMEM11	BNIP3
Gene Name		transmembrane protein 11	BCL2/adenovirus E1B 19kDa interacting protein 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Integral Component Of Mitochondrial Inner Membrane	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Dendrite Integral Component Of Mitochondrial Outer Membrane Mitochondrial Membrane
	Molecular Function	Molecular_function Protein Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity GTPase Binding
	Biological Process	Mitochondrion Organization	Response To Hypoxia Apoptotic Process Cell Death Granzyme-mediated Apoptotic Signaling Pathway Positive Regulation Of Autophagy Negative Regulation Of Mitochondrial Fusion Viral Process Mitochondrial Protein Catabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Protein Complex Disassembly Mitochondrial Fragmentation Involved In Apoptotic Process Negative Regulation Of Membrane Potential Regulation Of Mitochondrial Membrane Permeability Autophagic Cell Death Brown Fat Cell Differentiation Neuron Apoptotic Process Defense Response To Virus Response To Hyperoxia Cellular Response To Hydrogen Peroxide Cellular Response To Mechanical Stimulus Cellular Response To Cobalt Ion Cellular Response To Hypoxia Reactive Oxygen Species Metabolic Process Positive Regulation Of Mitochondrial Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Mitochondrial Outer Membrane Permeabilization Toxin Transport Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: BNIP3 BNIP3L CLN8 SCMH1 SUV39H1	15 interactors: BCL2 BCL2L1 BNIP3L CD47 CLEC7A CLN8 FATE1 HIVEP1 KTN1 LDLRAD1 MAP1LC3B NCBP1 RHEB TGM2 TMEM11
Entrez ID		8834	664
HPRD ID		12680	04482
Ensembl ID
Uniprot IDs		P17152	Q12983
PDB IDs			2J5D 2KA1 2KA2
Enriched GO Terms of Interacting Partners?		Mitochondrial Protein Catabolic Process Mitochondrial Membrane Organization Mitochondrial Outer Membrane Permeabilization Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Organelle Organization Mitochondrion Organization Apoptotic Mitochondrial Changes Viral Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Gene Silencing Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Cellular Response To Oxygen Levels L-glutamate Uptake Involved In Synaptic Transmission Mitochondrial Transport Cellular Macromolecule Catabolic Process Membrane Organization Defense Response To Virus Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Negative Regulation Of Mitochondrial Fusion Granzyme-mediated Apoptotic Signaling Pathway Autophagic Cell Death Age-dependent Response To Oxidative Stress Regulation Of Mitochondrial Fusion Response To Virus Histone H3-K9 Dimethylation Cellular Response To Cobalt Ion Response To Hypoxia Somatic Motor Neuron Differentiation L-glutamate Import Positive Regulation Of Mitochondrial Fission Mitochondrial Fragmentation Involved In Apoptotic Process Response To Stress Apoptotic Signaling Pathway Regulation Of Apoptotic Process Histone H3-K9 Trimethylation Peptidyl-lysine Dimethylation Regulation Of Cell Death Regulation Of Mitochondrial Fission Neurotransmitter Uptake Negative Regulation Of Membrane Potential Neurofilament Cytoskeleton Organization	Mitochondrion Organization Mitochondrial Membrane Organization Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Apoptotic Mitochondrial Changes Response To Other Organism Negative Regulation Of Anoikis Response To Biotic Stimulus Regulation Of Anoikis Membrane Organization Mitochondrial Transport Release Of Cytochrome C From Mitochondria Negative Regulation Of Autophagy Regulation Of Mitochondrial Membrane Potential Endoplasmic Reticulum Calcium Ion Homeostasis Response To External Stimulus Positive Regulation Of Apoptotic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Programmed Cell Death Transport Positive Regulation Of Cell Death Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Virus Endocytosis Response To Gamma Radiation Phagocytosis Neuron Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Neuron Death Negative Regulation Of Cellular PH Reduction CD8-positive, Alpha-beta T Cell Lineage Commitment Apoptotic Process In Bone Marrow Negative Regulation Of Retinal Cell Programmed Cell Death Ovarian Follicle Development Regulation Of Apoptotic Process Positive Regulation Of Intracellular Signal Transduction Apoptotic Signaling Pathway Positive Regulation Of Cell Proliferation Regulation Of Cell Death Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Stress Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine L-glutamate Uptake Involved In Synaptic Transmission Negative Regulation Of Apoptotic Process Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Programmed Cell Death Positive Regulation Of Inflammatory Response Ovulation Cycle Process
Tagcloud ?			accepted atg autophagy biomedical carbohydrate comprehensive discovery distributed diverse elucidating families great interest interesting lectins modulating origin perspective pharmacological plant problems raf representative respect summarize thousands ubiquitously widely working
Tagcloud (Difference) ?			accepted atg autophagy biomedical carbohydrate comprehensive discovery distributed diverse elucidating families great interest interesting lectins modulating origin perspective pharmacological plant problems raf representative respect summarize thousands ubiquitously widely working
Tagcloud (Intersection) ?