TMEM11 and RIC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM11	RIC3
Description		transmembrane protein 11	RIC3 acetylcholine receptor chaperone
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle Synapse
	Molecular Function	Protein Binding	Protein Binding Acetylcholine Receptor Binding Protein Folding Chaperone
	Biological Process	Mitochondrion Organization Inner Mitochondrial Membrane Organization	Protein Folding Positive Regulation Of Cytosolic Calcium Ion Concentration Synaptic Transmission, Cholinergic Protein Localization To Cell Surface Protein-containing Complex Assembly Positive Regulation Of Protein Localization To Cell Surface
Pathways		Cristae formation
Drugs			Theophylline
Diseases
GWAS		Body mass index ( 26426971) Metabolite levels ( 23823483)	Blood protein levels ( 30072576) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Malaria ( 31844061)
Interacting Genes		56 interacting genes: AQP6 ARL13B BDKRB2 BIK BNIP3 BNIP3L CCDC70 CCR4 CD79A CLDN7 CLN8 CREB3L1 CYB561 CYB5D2 DRD2 EBP ELOVL4 ERGIC3 FAM174A FAM209A FAM210B FATE1 FFAR2 GJB4 GORAB GPX8 KASH5 LEPROTL1 LMNA MRM1 MSMO1 MTIF3 MUC1 NDUFS3 OTX2 PDZK1IP1 PEX12 RETREG3 RIC3 RNASEH1 SCMH1 SGCB SLC10A6 SLC30A8 SUSD3 SUV39H1 TEX29 TMEM106C TMEM14B TMEM205 TMEM237 TMEM88 TMIE TMPRSS2 TNFSF14 YIPF6	16 interacting genes: BCL2L1 CACNA1C CLN6 FA2H FATE1 GOSR2 NINJ2 PRB1 STX12 STX7 TMBIM1 TMEFF2 TMEM11 TMEM86A TRAF3IP3 YIF1A
Entrez ID		8834	79608
HPRD ID		12680	17974
Ensembl ID		ENSG00000178307	ENSG00000166405
Uniprot IDs		P17152	A0A0S2Z607 A0A0S2Z6D3 B7Z3Z0 Q7Z5B4
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Endoplasmic Reticulum-autophagosome Adaptor Activity	Membrane SNARE Complex SNAP Receptor Activity Membrane Organization Endoplasmic Reticulum SNARE Binding Vesicle Fusion Organelle Membrane Fusion Regulation Of Protein Localization To Plasma Membrane Organelle Fusion Golgi Membrane Endoplasmic Reticulum Membrane Regulation Of Protein Localization To Cell Periphery Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Protein Localization To Plasma Membrane Membrane Fusion Regulation Of Protein Localization To Membrane Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Apoptotic Process In Bone Marrow Cell Mitochondrial Outer Membrane Negative Regulation Of Integrin Biosynthetic Process 4-hydroxysphinganine Ceramide Fatty Acyl 2-hydroxylase Activity Free Fatty Acid 2-hydroxylase Activity Fatty Acid 2-hydroxylase Activity Glycosphingolipid Metabolic Process Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Endomembrane System Vesicle Docking Negative Regulation Of Fas Signaling Pathway Sebaceous Gland Cell Differentiation Glucosylceramide Biosynthetic Process Regulation Of Sebum Secreting Cell Proliferation Regulation Of Acinar Cell Proliferation Alkenylglycerophosphocholine Hydrolase Activity Dendritic Cell Proliferation Dendritic Cell Apoptotic Process Membrane Depolarization During Atrial Cardiac Muscle Cell Action Potential Calcium Channel Activity Voltage-gated Calcium Channel Activity Involved In AV Node Cell Action Potential Voltage-gated Calcium Channel Activity Involved In Cardiac Muscle Cell Action Potential Vesicle Organization Tertiary Granule Organelle Localization By Membrane Tethering Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Central Nervous System Myelin Maintenance Membrane Docking Vesicle-mediated Transport Membrane Destabilizing Activity Positive Regulation Of Receptor Localization To Synapse Glycolipid Metabolic Process
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