BNIP3

Gene Name		BCL2/adenovirus E1B 19kDa interacting protein 3
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Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Dendrite Integral Component Of Mitochondrial Outer Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity GTPase Binding
	Biological Process	Response To Hypoxia Apoptotic Process Cell Death Granzyme-mediated Apoptotic Signaling Pathway Positive Regulation Of Autophagy Negative Regulation Of Mitochondrial Fusion Viral Process Mitochondrial Protein Catabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Protein Complex Disassembly Mitochondrial Fragmentation Involved In Apoptotic Process Negative Regulation Of Membrane Potential Regulation Of Mitochondrial Membrane Permeability Autophagic Cell Death Brown Fat Cell Differentiation Neuron Apoptotic Process Defense Response To Virus Response To Hyperoxia Cellular Response To Hydrogen Peroxide Cellular Response To Mechanical Stimulus Cellular Response To Cobalt Ion Cellular Response To Hypoxia Reactive Oxygen Species Metabolic Process Positive Regulation Of Mitochondrial Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Mitochondrial Outer Membrane Permeabilization Toxin Transport Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		15 interactors: BCL2 BCL2L1 BNIP3L CD47 CLEC7A CLN8 FATE1 HIVEP1 KTN1 LDLRAD1 MAP1LC3B NCBP1 RHEB TGM2 TMEM11
Entrez ID		664
HPRD ID		04482
Ensembl ID
Uniprot IDs		Q12983
PDB IDs		2J5D 2KA1 2KA2
Enriched GO Terms of Interacting Partners?		Mitochondrion Organization Mitochondrial Membrane Organization Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Apoptotic Mitochondrial Changes Response To Other Organism Negative Regulation Of Anoikis Response To Biotic Stimulus Regulation Of Anoikis Membrane Organization Mitochondrial Transport Release Of Cytochrome C From Mitochondria Negative Regulation Of Autophagy Regulation Of Mitochondrial Membrane Potential Endoplasmic Reticulum Calcium Ion Homeostasis Response To External Stimulus Positive Regulation Of Apoptotic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Programmed Cell Death Transport Positive Regulation Of Cell Death Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Virus Endocytosis Response To Gamma Radiation Phagocytosis Neuron Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Neuron Death Negative Regulation Of Cellular PH Reduction CD8-positive, Alpha-beta T Cell Lineage Commitment Apoptotic Process In Bone Marrow Negative Regulation Of Retinal Cell Programmed Cell Death Ovarian Follicle Development Regulation Of Apoptotic Process Positive Regulation Of Intracellular Signal Transduction Apoptotic Signaling Pathway Positive Regulation Of Cell Proliferation Regulation Of Cell Death Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Stress Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine L-glutamate Uptake Involved In Synaptic Transmission Negative Regulation Of Apoptotic Process Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Programmed Cell Death Positive Regulation Of Inflammatory Response Ovulation Cycle Process
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