MPDZ and CLDN5

Number of citations of the paper that reports this interaction (PMID 12403818)
35

Data Source:
HPRD (in vivo)

		MPDZ	CLDN5
Gene Name		multiple PDZ domain protein	claudin 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Tight Junction Postsynaptic Density Apical Plasma Membrane Apicolateral Plasma Membrane Dendrite Cytoplasmic Vesicle Schmidt-Lanterman Incisure Postsynaptic Membrane	Plasma Membrane Cell-cell Junction Tight Junction Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein C-terminus Binding	Structural Molecule Activity Identical Protein Binding
	Biological Process	Cell Adhesion Viral Process Myelination	Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Pathways			Cell junction organization Cell-cell junction organization Tight junction interactions
Drugs
Diseases
GWAS		Corneal structure ( 23291589)
Protein-Protein Interactions		13 interactors: ABCA1 CAMK2A CLDN1 CLDN5 CSPG4 DRD3 F11R HTR2C KIT PLEKHA1 PLEKHA2 RNF5 SYNGAP1	3 interactors: CLDN3 MPDZ TJP1
Entrez ID		8777	7122
HPRD ID		09155	03654
Ensembl ID		ENSG00000107186	ENSG00000184113
Uniprot IDs		F5H1U9 O75970	D3DX19 O00501
PDB IDs		2FCF 2FNE 2IWN 2IWO 2IWP 2IWQ 2O2T 2OPG 2QG1
Enriched GO Terms of Interacting Partners?		Regulation Of Intracellular Signal Transduction Regulation Of Neuronal Synaptic Plasticity Regulation Of Signaling Visual Learning Visual Behavior Associative Learning Regulation Of Synaptic Transmission Regulation Of Signal Transduction Learning Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Response To Radiation Single-organism Behavior Regulation Of Synaptic Plasticity Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Membrane Permeability Response To Abiotic Stimulus Negative Regulation Of Protein Kinase B Signaling Behavior Regulation Of MAPK Cascade Cellular Response To Stimulus Signal Transduction Learning Or Memory Cognition Negative Regulation Of Cell Differentiation Regulation Of Lipid Metabolic Process Homeostatic Process Rhythmic Process Mast Cell Cytokine Production Melanocyte Adhesion Dendritic Cell Cytokine Production Mast Cell Proliferation Signaling Response To Light Stimulus Cell Communication Membrane Organization Chemical Homeostasis Positive Regulation Of Metabolic Process Cellular Localization Response To Stress Regulation Of Cell Differentiation Regulation Of CAMP Biosynthetic Process Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Sodium:proton Antiporter Activity Regulation Of Corticotropin-releasing Hormone Secretion Gastric Emptying Kit Signaling Pathway Erythropoietin-mediated Signaling Pathway Phospholipase C-activating Serotonin Receptor Signaling Pathway	Cell-cell Signaling Involved In Cell-cell Junction Organization Epithelial Cell Development Response To Magnetism Establishment Of Endothelial Intestinal Barrier Epithelial Cell Differentiation Negative Regulation Of Vascular Permeability Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Establishment Of Endothelial Barrier Hippo Signaling Regulation Of Vascular Permeability Blastocyst Formation Endothelial Cell Development Epithelium Development Response To Abiotic Stimulus Epithelial Cell Morphogenesis Cell Adhesion Cellular Response To Glucose Stimulus Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Anatomical Structure Development Execution Phase Of Apoptosis Cellular Glucose Homeostasis Cellular Response To Carbohydrate Stimulus Endothelial Cell Differentiation Endothelium Development Developmental Process Blastocyst Development Cell-cell Junction Assembly Tissue Development Response To Glucose Cell Development Response To Ethanol Myelination Axon Ensheathment Sensory Perception Of Sound
Tagcloud ?		a4 ace2 affective affectivity bonferroni combine converting correction endoperoxide exceeded gated nociceptive nonspecific oppera orofacial phenotypes prostaglandin ptgs1 rs10809907 rs1514280 rs3842803 rs466448 rs6432860 scn1a summation temporomandibular thresholds tmd	22q11 ccdd cranial duane dup22q11 duplicated duplication dysinnervation expand glaucoma gunn infantile jaw manifestation mapk1 marcus movements ocular oligo ophthalmologic physiopathology retinal retraction segment semaphorin snap29 tortuosity unreported winking
Tagcloud (Difference) ?		a4 ace2 affective affectivity bonferroni combine converting correction endoperoxide exceeded gated nociceptive nonspecific oppera orofacial phenotypes prostaglandin ptgs1 rs10809907 rs1514280 rs3842803 rs466448 rs6432860 scn1a summation temporomandibular thresholds tmd	22q11 ccdd cranial duane dup22q11 duplicated duplication dysinnervation expand glaucoma gunn infantile jaw manifestation mapk1 marcus movements ocular oligo ophthalmologic physiopathology retinal retraction segment semaphorin snap29 tortuosity unreported winking
Tagcloud (Intersection) ?