CLDN5 and YIPF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLDN5	YIPF1
Description		claudin 5	Yip1 domain family member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Membrane Apicolateral Plasma Membrane Lateral Plasma Membrane Cell Junction Cortical Actin Cytoskeleton Paranode Region Of Axon Schmidt-Lanterman Incisure Tight Junction Anchoring Junction	Golgi Trans Cisterna Nucleoplasm Endosome Golgi Apparatus Golgi Medial Cisterna Trans-Golgi Network Plasma Membrane Endomembrane System Membrane Transport Vesicle Late Endosome Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding	Protein Binding Small GTPase Binding
	Biological Process	Outflow Tract Morphogenesis Cell-cell Junction Assembly Cell Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Learning Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration Maintenance Of Blood-brain Barrier Myelination Negative Regulation Of Vascular Permeability Response To Ethanol Roof Of Mouth Development Face Morphogenesis Bicellular Tight Junction Assembly Tight Junction Assembly Positive Regulation Of Establishment Of Endothelial Barrier Positive Regulation Of Bicellular Tight Junction Assembly Establishment Of Blood-retinal Barrier	Vesicle-mediated Transport
Pathways		Tight junction interactions RUNX1 regulates expression of components of tight junctions
Drugs
Diseases
GWAS			Nonalcoholic fatty liver disease ( 22719876)
Interacting Genes		40 interacting genes: AQP1 BTNL8 CCDC167 CLDN3 CLRN2 CNPY3 CORIN CTRL CXCL9 CYB561A3 EFNA5 EHHADH ERG28 ERMP1 FXYD6-FXYD2 GYPA LAT LHFPL5 MIP MPDZ PLP2 PLPPR2 PMP22 RPRM SFTPC SGCG SLC35B4 SMIM3 TECR TF TJP1 TMEM128 TMEM140 TMEM14C TMEM182 TMEM190 TMEM222 TSPAN2 VAMP5 YIPF1	35 interacting genes: APCDD1L AQP6 ASGR2 CLDN5 CMTM2 CNR2 EBP ERGIC3 F2RL1 FFAR3 GPR152 GPR42 GPRC5D KCNJ6 LEPROT LINC00839 LMNA RETREG3 RNF5 SIGLEC12 SLC10A6 SLC18A1 SLC35G1 SLC71A2 SLC7A8 TIMMDC1 TLCD4 TMEM14B TMEM248 TMPPE TMX2 TVP23B VMA21 YIPF6 ZDHHC7
Entrez ID		7122	54432
HPRD ID		03654	13147
Ensembl ID		ENSG00000184113	ENSG00000058799
Uniprot IDs		D3DX19 O00501	Q9Y548
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Endoplasmic Reticulum G Protein-coupled Receptor Activity
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