CLDN5 and CLDN3

Number of citations of the paper that reports this interaction (PMID 12909588)
67

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		CLDN5	CLDN3
Gene Name		claudin 5	claudin 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Tight Junction Integral Component Of Membrane Extracellular Vesicular Exosome	Integral Component Of Plasma Membrane Tight Junction Integral Component Of Membrane Lateral Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Structural Molecule Activity Identical Protein Binding	Transmembrane Signaling Receptor Activity Structural Molecule Activity Identical Protein Binding
	Biological Process	Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules	Response To Hypoxia Epithelial Cell Morphogenesis Signal Transduction Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Pathways		Cell junction organization Cell-cell junction organization Tight junction interactions	Cell junction organization Cell-cell junction organization Tight junction interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CLDN3 MPDZ TJP1	7 interactors: APP CLDN1 CLDN5 POM121 PRKACA TJP1 WNK4
Entrez ID		7122	1365
HPRD ID		03654	04219
Ensembl ID		ENSG00000184113	ENSG00000165215
Uniprot IDs		D3DX19 O00501	O15551 Q75L79
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Involved In Cell-cell Junction Organization Epithelial Cell Development Response To Magnetism Establishment Of Endothelial Intestinal Barrier Epithelial Cell Differentiation Negative Regulation Of Vascular Permeability Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Establishment Of Endothelial Barrier Hippo Signaling Regulation Of Vascular Permeability Blastocyst Formation Endothelial Cell Development Epithelium Development Response To Abiotic Stimulus Epithelial Cell Morphogenesis Cell Adhesion Cellular Response To Glucose Stimulus Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Anatomical Structure Development Execution Phase Of Apoptosis Cellular Glucose Homeostasis Cellular Response To Carbohydrate Stimulus Endothelial Cell Differentiation Endothelium Development Developmental Process Blastocyst Development Cell-cell Junction Assembly Tissue Development Response To Glucose Cell Development Response To Ethanol Myelination Axon Ensheathment Sensory Perception Of Sound	Chemical Homeostasis Homeostatic Process Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell-cell Junction Organization Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Multicellular Organismal Water Homeostasis Cellular Response To Glucose Stimulus Water Homeostasis Nuclear Envelope Organization Cell Adhesion Cellular Glucose Homeostasis Cellular Response To Carbohydrate Stimulus Cell-cell Signaling Involved In Cell-cell Junction Organization Positive Regulation Of Dense Core Granule Biogenesis Renal System Process Regulation Of Glucose Transport Cellular Chemical Homeostasis Multicellular Organismal Development Ion Homeostasis Anatomical Structure Development Regulation Of Body Fluid Levels Positive Regulation Of Mitotic Cell Cycle Cell-cell Junction Assembly Nucleus Organization Synaptic Growth At Neuromuscular Junction Histone H3-T6 Phosphorylation Response To Glucose Regulation Of Protein Binding Cell Maturation Cellular Homeostasis Distal Tubule Morphogenesis Collateral Sprouting In Absence Of Injury Developmental Process Renal Sodium Ion Absorption Response To Magnetism Response To Carbohydrate Platelet Activation Collateral Sprouting Negative Regulation Of Pancreatic Juice Secretion Renal Sodium Ion Transport Axon Midline Choice Point Recognition Cell Junction Assembly Membrane Organization Glucose Homeostasis Pathogenesis Regulation Of Peptidyl-tyrosine Phosphorylation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Cell Cycle Process Peptidyl-serine Autophosphorylation
Tagcloud ?		22q11 ccdd cranial duane dup22q11 duplicated duplication dysinnervation expand glaucoma gunn infantile jaw manifestation mapk1 marcus movements ocular oligo ophthalmologic physiopathology retinal retraction segment semaphorin snap29 tortuosity unreported winking	anat asmt characterise circumventricular col11a1 cvos epcam ependyma ependymocytes lcm microdissection organum ovlt peculiar periventricular pineal ren1 sco sfo slc22a3 specialised subcommissural subfornical terminalis tph transcriptomes vasculosum ventricles vestigial
Tagcloud (Difference) ?		22q11 ccdd cranial duane dup22q11 duplicated duplication dysinnervation expand glaucoma gunn infantile jaw manifestation mapk1 marcus movements ocular oligo ophthalmologic physiopathology retinal retraction segment semaphorin snap29 tortuosity unreported winking	anat asmt characterise circumventricular col11a1 cvos epcam ependyma ependymocytes lcm microdissection organum ovlt peculiar periventricular pineal ren1 sco sfo slc22a3 specialised subcommissural subfornical terminalis tph transcriptomes vasculosum ventricles vestigial
Tagcloud (Intersection) ?