CTNNAL1 and AKAP13

Number of citations of the paper that reports this interaction (PMID 12270917)
16

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (in vivo, two hybrid, in vitro)

		CTNNAL1	AKAP13
Gene Name		catenin (cadherin-associated protein), alpha-like 1	A kinase (PRKA) anchor protein 13
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane	Nucleus Cytoplasm Cytosol Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Cadherin Binding Actin Filament Binding	CAMP-dependent Protein Kinase Activity Signal Transducer Activity Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding Rho GTPase Binding Protein Complex Scaffold Metal Ion Binding Protein Kinase A Binding
	Biological Process	Cell Adhesion Rho Protein Signal Transduction	Protein Phosphorylation Small GTPase Mediated Signal Transduction Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Rho GTPase Activity Positive Regulation Of Apoptotic Process Regulation Of Protein Kinase Activity Neurotrophin TRK Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Nuclear Export Apoptotic Signaling Pathway Regulation Of Glucocorticoid Mediated Signaling Pathway
Pathways			Rho GTPase cycle Signaling by GPCR GPCR downstream signaling Signalling by NGF Cell death signalling via NRAGE, NRIF and NADE Signaling by Rho GTPases NRAGE signals death through JNK G alpha (12/13) signalling events p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS			Central corneal thickness ( 20719862) Corneal structure ( 23291589)
Protein-Protein Interactions		9 interactors: AKAP13 C19orf57 CALU DMD NEK1 PCGF2 RNF135 SPERT USH1C	20 interactors: CTNNAL1 DYT10 ESR1 ESR2 GNA12 GNAQ MAP1LC3A PPARA PRKACA PRKAR2A PRKD1 RANBP2 RHOA RTKN RXRB THRA YWHAB YWHAE YWHAG YWHAZ
Entrez ID		8727	11214
HPRD ID		09210	05253
Ensembl ID		ENSG00000119326	ENSG00000170776
Uniprot IDs		Q9UBT7	B0AZU4 Q12802
PDB IDs			2DRN 2LG1
Enriched GO Terms of Interacting Partners?			Cell Communication Signal Transduction Cellular Response To Stimulus Cellular Response To Organic Substance Signaling Cellular Response To Hormone Stimulus Regulation Of Intracellular Transport Regulation Of Establishment Of Protein Localization Response To Stimulus Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Protein Localization Response To Organic Substance Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Steroid Hormone Mediated Signaling Pathway Response To Hormone Positive Regulation Of Intracellular Transport Intracellular Signal Transduction Regulation Of Cellular Localization Hormone-mediated Signaling Pathway Positive Regulation Of Phospholipase C Activity Rho Protein Signal Transduction Positive Regulation Of Mitochondrion Organization Transcription Initiation From RNA Polymerase II Promoter Apoptotic Signaling Pathway Cellular Response To Steroid Hormone Stimulus Wound Healing Intrinsic Apoptotic Signaling Pathway Intracellular Receptor Signaling Pathway Positive Regulation Of Phospholipase Activity Platelet Activation Apoptotic Process Cellular Response To Organic Cyclic Compound Regulation Of Signaling Programmed Cell Death Positive Regulation Of Organelle Organization Neurotrophin TRK Receptor Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Phospholipase Activity Response To Wounding Positive Regulation Of Lipase Activity Ras Protein Signal Transduction Blood Coagulation Cell Death Death Neurotrophin Signaling Pathway Hemostasis DNA-templated Transcription, Initiation Regulation Of Mitochondrion Organization Negative Regulation Of Kinase Activity
Tagcloud ?		architecture array became clarify claudins cldn17 cldns contradictory decades downregulated ductal efforts eighteen enormous forty invasive jam junctions luminal mentioned pard3 past surrogate ten tendency tight tj tjs zo	anchoring assume bifunctional bundle causation chair crisis dbl deregulated dh dynamical explains gdp gef gtpase guanine helical hyperactive lbc linker mediation onco pleckstrin possessing rhoa rigid scattering seat solitary
Tagcloud (Difference) ?		architecture array became clarify claudins cldn17 cldns contradictory decades downregulated ductal efforts eighteen enormous forty invasive jam junctions luminal mentioned pard3 past surrogate ten tendency tight tj tjs zo	anchoring assume bifunctional bundle causation chair crisis dbl deregulated dh dynamical explains gdp gef gtpase guanine helical hyperactive lbc linker mediation onco pleckstrin possessing rhoa rigid scattering seat solitary
Tagcloud (Intersection) ?