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AKAP13
Gene Name
A kinase (PRKA) anchor protein 13
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Membrane
Perinuclear Region Of Cytoplasm
Molecular Function
CAMP-dependent Protein Kinase Activity
Signal Transducer Activity
Rho Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Rho GTPase Binding
Protein Complex Scaffold
Metal Ion Binding
Protein Kinase A Binding
Biological Process
Protein Phosphorylation
Small GTPase Mediated Signal Transduction
Regulation Of Cardiac Muscle Hypertrophy
Positive Regulation Of Rho GTPase Activity
Positive Regulation Of Apoptotic Process
Regulation Of Protein Kinase Activity
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Small GTPase Mediated Signal Transduction
Nuclear Export
Apoptotic Signaling Pathway
Regulation Of Glucocorticoid Mediated Signaling Pathway
Pathways
Rho GTPase cycle
Signaling by GPCR
GPCR downstream signaling
Signalling by NGF
Cell death signalling via NRAGE, NRIF and NADE
Signaling by Rho GTPases
NRAGE signals death through JNK
G alpha (12/13) signalling events
p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS
Central corneal thickness (
20719862
)
Corneal structure (
23291589
)
Protein-protein Interactions
20 interactors:
CTNNAL1
DYT10
ESR1
ESR2
GNA12
GNAQ
MAP1LC3A
PPARA
PRKACA
PRKAR2A
PRKD1
RANBP2
RHOA
RTKN
RXRB
THRA
YWHAB
YWHAE
YWHAG
YWHAZ
Entrez ID
11214
HPRD ID
05253
Ensembl ID
ENSG00000170776
Uniprot IDs
B0AZU4
Q12802
PDB IDs
2DRN
2LG1
Enriched GO Terms of Interacting Partners
?
Cell Communication
Signal Transduction
Cellular Response To Stimulus
Cellular Response To Organic Substance
Signaling
Cellular Response To Hormone Stimulus
Regulation Of Intracellular Transport
Regulation Of Establishment Of Protein Localization
Response To Stimulus
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Regulation Of Protein Localization
Response To Organic Substance
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Steroid Hormone Mediated Signaling Pathway
Response To Hormone
Positive Regulation Of Intracellular Transport
Intracellular Signal Transduction
Regulation Of Cellular Localization
Hormone-mediated Signaling Pathway
Positive Regulation Of Phospholipase C Activity
Rho Protein Signal Transduction
Positive Regulation Of Mitochondrion Organization
Transcription Initiation From RNA Polymerase II Promoter
Apoptotic Signaling Pathway
Cellular Response To Steroid Hormone Stimulus
Wound Healing
Intrinsic Apoptotic Signaling Pathway
Intracellular Receptor Signaling Pathway
Positive Regulation Of Phospholipase Activity
Platelet Activation
Apoptotic Process
Cellular Response To Organic Cyclic Compound
Regulation Of Signaling
Programmed Cell Death
Positive Regulation Of Organelle Organization
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Cellular Component Organization
Regulation Of Phospholipase Activity
Response To Wounding
Positive Regulation Of Lipase Activity
Ras Protein Signal Transduction
Blood Coagulation
Cell Death
Death
Neurotrophin Signaling Pathway
Hemostasis
DNA-templated Transcription, Initiation
Regulation Of Mitochondrion Organization
Negative Regulation Of Kinase Activity
Tagcloud
?
anchoring
assume
bifunctional
bundle
causation
chair
crisis
dbl
deregulated
dh
dynamical
explains
gdp
gef
gtpase
guanine
helical
hyperactive
lbc
linker
mediation
onco
pleckstrin
possessing
rhoa
rigid
scattering
seat
solitary