CTNNAL1 and CALU

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		CTNNAL1	CALU
Description		catenin alpha like 1	calumenin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Sarcoplasmic Reticulum Sarcoplasmic Reticulum Lumen Melanosome
	Molecular Function	Protein Binding Cadherin Binding Actin Filament Binding	Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Cell Adhesion Rho Protein Signal Transduction
Pathways			Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS			Atrial fibrillation ( 30061737) Intelligence (MTAG) ( 29326435) Moderate to vigorous physical activity levels ( 29899525) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397) Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552)
Interacting Genes		11 interacting genes: AKAP13 BRME1 CALU DMD NEK1 PCGF2 SERTAD3 TRIM7 TSC22D4 USH1C ZBED1	11 interacting genes: APCS CEBPA CSNK2A1 CTNNAL1 MFHAS1 PRMT5 SNCA UBE2I UBQLN1 UMPS ZPBP
Entrez ID		8727	813
HPRD ID		09210	04569
Ensembl ID		ENSG00000119326	ENSG00000128595
Uniprot IDs		B3KMX6 Q9UBT7	B3KQF5 O43852 Q6IAW5
PDB IDs
Enriched GO Terms of Interacting Partners?			Regulation Of Macrophage Activation Identical Protein Binding Aggrephagy Regulation Of Defense Response Regulation Of Inflammatory Response Regulation Of Protein Catabolic Process Acute-phase Response Negative Regulation Of Immune System Process Cellular Component Assembly Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Catabolic Process Animal Organ Regeneration RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Protein Catabolic Process Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission SUMO Conjugating Enzyme Activity Orotidine-5'-phosphate Decarboxylase Activity Orotate Phosphoribosyltransferase Activity Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Negative Regulation Of Store-operated Calcium Channel Activity Acute Inflammatory Response Protein-containing Complex Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Response To Vitamin B2 C/EBP Complex Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Peptidyl-arginine N-methylation Regulation Of Immune System Process Regulation Of Protein Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Kinase Binding CHOP-C/EBP Complex Regulation Of Proteolysis Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Autophagy Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy RING-like Zinc Finger Domain Binding 'de Novo' UMP Biosynthetic Process Histone Arginine N-methyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Negative Regulation Of Toll-like Receptor 3 Signaling Pathway
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