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S1PR4 and GNAI1
Number of citations of the paper that reports this interaction (PMID
12761884
)
14
Data Source:
HPRD
(in vitro)
S1PR4
GNAI1
Gene Name
sphingosine-1-phosphate receptor 4
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
Image
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Nucleus
Cytoplasm
Lysosomal Membrane
Centrosome
Heterotrimeric G-protein Complex
Plasma Membrane
Midbody
Extracellular Vesicular Exosome
Molecular Function
G-protein Coupled Receptor Activity
Lipid Binding
Sphingosine-1-phosphate Receptor Activity
GTPase Activity
Signal Transducer Activity
Protein Binding
GTP Binding
G-protein Beta/gamma-subunit Complex Binding
G-protein Coupled Serotonin Receptor Binding
Metal Ion Binding
Biological Process
Sphingosine-1-phosphate Signaling Pathway
Immune Response
G-protein Coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway
Activation Of Phospholipase C Activity
Positive Regulation Of Cytosolic Calcium Ion Concentration
Cell Cycle
G-protein Coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Synaptic Transmission
Blood Coagulation
Platelet Activation
Response To Peptide Hormone
Cell Division
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
GPCR downstream signaling
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Lysosphingolipid and LPA receptors
Signaling by GPCR
Integration of energy metabolism
G alpha (s) signalling events
Activation of GABAB receptors
Signal amplification
G alpha (z) signalling events
G alpha (i) signalling events
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
ADP signalling through P2Y purinoceptor 12
GABA B receptor activation
Adenylate cyclase inhibitory pathway
GABA receptor activation
PLC beta mediated events
Opioid Signalling
Regulation of insulin secretion
G-protein mediated events
Adrenaline,noradrenaline inhibits insulin secretion
Inhibition of adenylate cyclase pathway
Adenylate cyclase inhibitory pathway
GPCR downstream signaling
G-protein activation
Platelet activation, signaling and aggregation
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions
3 interactors:
GNA12
GNA13
GNAI1
57 interactors:
ADCY5
ADRA2A
CCR5
CD47
CNR1
CRHR1
CXCR4
DRD3
EPOR
ESR1
FFAR1
GNAO1
GNB2
GNB4
GPR1
GPR143
GPSM1
GPSM2
GPSM3
HRH4
HTR2A
IGF1R
KLHL3
MTNR1A
MTNR1B
NGB
NUCB1
NUMA1
OPRD1
OPRM1
PDE6D
PTPRU
RANGAP1
RASD1
RGS10
RGS12
RGS14
RGS16
RGS17
RGS18
RGS19
RGS20
RGS4
RGS7
RIC8A
S1PR1
S1PR2
S1PR3
S1PR4
S1PR5
SSTR2
SSTR3
STRN
THAP7
TSHR
VIPR1
WASF1
Entrez ID
8698
2770
HPRD ID
04779
00756
Ensembl ID
ENSG00000125910
ENSG00000127955
Uniprot IDs
O95977
P63096
PDB IDs
2DCO
1KJY
1Y3A
2G83
2GTP
2IK8
2OM2
2PZ3
2XNS
3ONW
3QE0
3QI2
3UMR
3UMS
4G5Q
Enriched GO Terms of Interacting Partners
?
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Platelet Activation
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Wound Healing
Rho Protein Signal Transduction
Cell Activation
Response To Wounding
G-protein Coupled Receptor Signaling Pathway
Regulation Of Cell Shape
Ras Protein Signal Transduction
Regulation Of Cell Morphogenesis
In Utero Embryonic Development
Regulation Of Cell Migration
Activation Of Phospholipase D Activity
Small GTPase Mediated Signal Transduction
Regulation Of Cell Motility
Cell Surface Receptor Signaling Pathway
Regulation Of Locomotion
Regulation Of Cellular Component Movement
Response To Stress
Chordate Embryonic Development
Embryo Development Ending In Birth Or Egg Hatching
Regulation Of Fibroblast Migration
Patterning Of Blood Vessels
Vesicle Fusion
Embryo Development
Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Regulation Of TOR Signaling
Embryonic Digit Morphogenesis
Organelle Fusion
Positive Regulation Of Phospholipase Activity
Regulation Of Phospholipase Activity
Signal Transduction
Positive Regulation Of Lipase Activity
Signaling
Cell Communication
Membrane Fusion
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Intracellular Signal Transduction
Regulation Of Cellular Component Organization
Positive Regulation Of Cytosolic Calcium Ion Concentration
Embryonic Limb Morphogenesis
G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Cell Surface Receptor Signaling Pathway
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Signal Transduction
Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Signaling
Cell Communication
Regulation Of Catalytic Activity
Termination Of G-protein Coupled Receptor Signaling Pathway
Termination Of Signal Transduction
Cellular Response To Stimulus
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Catalytic Activity
Response To Stimulus
Regulation Of Signaling
Positive Regulation Of Hydrolase Activity
Positive Regulation Of Cytosolic Calcium Ion Concentration
Sphingosine-1-phosphate Signaling Pathway
Regulation Of Cellular Process
Chemical Homeostasis
Cell-cell Signaling
Cytosolic Calcium Ion Homeostasis
Positive Regulation Of GTPase Activity
Cellular Calcium Ion Homeostasis
Calcium Ion Homeostasis
Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
Regulation Of GTPase Activity
Positive Regulation Of Metabolic Process
Regulation Of Signal Transduction
Synaptic Transmission
Negative Regulation Of Signaling
Behavior
Cellular Metal Ion Homeostasis
Neuropeptide Signaling Pathway
Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway
Cellular Cation Homeostasis
Ion Homeostasis
Cellular Ion Homeostasis
Homeostatic Process
Metal Ion Homeostasis
Negative Regulation Of Signal Transduction
Cellular Chemical Homeostasis
Locomotory Behavior
Response To Ammonium Ion
Negative Regulation Of Ion Transport
Response To Cocaine
Regulation Of Cell Proliferation
Neurological System Process
Tagcloud
?
alkenes
azotic
constructions
gnao1
heterocycle
hm
hms
htr1b
htr2a
htr2b
htr4
htr6
htr7
kpnb1
pharmacopeia
prkaca
prkca
prkcb
prkcd
prkce
prkcg
prkd1
propertied
pubchem
rock2
rps6ka1
rps6ka3
tlr8
tradition
Tagcloud (Difference)
?
alkenes
azotic
constructions
gnao1
heterocycle
hm
hms
htr1b
htr2a
htr2b
htr4
htr6
htr7
kpnb1
pharmacopeia
prkaca
prkca
prkcb
prkcd
prkce
prkcg
prkd1
propertied
pubchem
rock2
rps6ka1
rps6ka3
tlr8
tradition
Tagcloud (Intersection)
?