S1PR4

Gene Name		sphingosine-1-phosphate receptor 4
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	G-protein Coupled Receptor Activity Lipid Binding Sphingosine-1-phosphate Receptor Activity
	Biological Process	Sphingosine-1-phosphate Signaling Pathway Immune Response G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Positive Regulation Of Cytosolic Calcium Ion Concentration
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: GNA12 GNA13 GNAI1
Entrez ID		8698
HPRD ID		04779
Ensembl ID		ENSG00000125910
Uniprot IDs		O95977
PDB IDs		2DCO
Enriched GO Terms of Interacting Partners?		Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Platelet Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Rho Protein Signal Transduction Cell Activation Response To Wounding G-protein Coupled Receptor Signaling Pathway Regulation Of Cell Shape Ras Protein Signal Transduction Regulation Of Cell Morphogenesis In Utero Embryonic Development Regulation Of Cell Migration Activation Of Phospholipase D Activity Small GTPase Mediated Signal Transduction Regulation Of Cell Motility Cell Surface Receptor Signaling Pathway Regulation Of Locomotion Regulation Of Cellular Component Movement Response To Stress Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Regulation Of Fibroblast Migration Patterning Of Blood Vessels Vesicle Fusion Embryo Development Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Regulation Of TOR Signaling Embryonic Digit Morphogenesis Organelle Fusion Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Signal Transduction Positive Regulation Of Lipase Activity Signaling Cell Communication Membrane Fusion Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Regulation Of Cellular Component Organization Positive Regulation Of Cytosolic Calcium Ion Concentration Embryonic Limb Morphogenesis
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