STX16 and VAMP3

Number of citations of the paper that reports this interaction (PMID 11839770)
115

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		STX16	VAMP3
Gene Name		syntaxin 16	vesicle-associated membrane protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleolus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Cytosol Focal Adhesion Endomembrane System Membrane Integral Component Of Membrane SNARE Complex Golgi Cisterna Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Intracellular Cytosol Plasma Membrane Synaptic Vesicle Cell Surface Integral Component Of Membrane Apical Plasma Membrane Cell Junction Clathrin-coated Vesicle Secretory Granule Clathrin-coated Vesicle Membrane SNARE Complex Neuron Projection Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin-1 Binding
	Biological Process	Intracellular Protein Transport Intra-Golgi Vesicle-mediated Transport Vesicle Fusion Retrograde Transport, Endosome To Golgi Vesicle Docking Golgi Ribbon Formation	Positive Regulation Of Receptor Recycling Protein Complex Assembly Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Neurotransmitter Secretion Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Substrate Adhesion-dependent Cell Spreading SNARE Complex Assembly Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Positive Regulation Of Immunoglobulin Secretion Membrane Fusion Mucus Secretion Negative Regulation Of Secretion By Cell Regulation Of Histamine Secretion By Mast Cell
Pathways
Drugs
Diseases
GWAS		Cardiovascular disease risk factors ( 20838585)	Crohn's disease ( 21102463) Periodontal microbiota ( 22699663)
Protein-Protein Interactions		10 interactors: MEOX2 NAPB PTPN12 STX4 STX6 VAMP3 VAMP4 VAMP5 VPS45 VTI1A	14 interactors: ACAP1 APP BCAP31 BCL2L13 DDB1 IKBKG NELFE SNAP23 STX16 STX2 STX3 STX4 VAMP2 VAMP8
Entrez ID		8675	9341
HPRD ID		04718	04711
Ensembl ID		ENSG00000124222	ENSG00000049245
Uniprot IDs		B4DJX9 O14662	Q15836 Q6FGG2 Q9BRV4
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Fusion Vesicle Fusion Organelle Fusion Vesicle Organization Golgi Ribbon Formation SNARE Complex Assembly Vesicle-mediated Transport Membrane Organization Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Golgi Vesicle Transport Establishment Of Localization In Cell Exocytosis Cellular Protein Localization Protein Transport Establishment Of Protein Localization Cellular Localization Intracellular Transport Endomembrane System Organization Secretion By Cell Protein Localization Retrograde Transport, Endosome To Golgi Secretion Golgi Organization Vesicle Docking Membrane Docking Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Golgi To Plasma Membrane Protein Transport Neurotransmitter Transport Endosomal Transport Golgi To Plasma Membrane Transport Transport Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Protein Localization To Plasma Membrane Vesicle Docking Involved In Exocytosis Cellular Protein Complex Assembly Establishment Of Protein Localization To Plasma Membrane Organelle Organization Positive Regulation Of Eosinophil Degranulation Skeletal Muscle Tissue Development Voluntary Musculoskeletal Movement Skeletal Muscle Organ Development Protein Localization To Plasma Membrane Cellular Macromolecular Complex Assembly SNARE Complex Disassembly Somite Specification Cytoplasmic Transport Positive Regulation Of Protein Localization To Cell Surface Golgi To Vacuole Transport	Vesicle Fusion Organelle Fusion Membrane Fusion Vesicle Organization Synaptic Vesicle Fusion To Presynaptic Membrane Synaptic Vesicle Exocytosis Exocytosis Establishment Of Vesicle Localization Vesicle Localization Neurotransmitter Secretion Synaptic Vesicle Transport Golgi Vesicle Transport Secretion By Cell Establishment Of Localization In Cell Regulation Of Neurotransmitter Levels Protein Transport Vesicle-mediated Transport Establishment Of Organelle Localization Establishment Of Protein Localization Intracellular Transport Secretion Neurotransmitter Transport Cellular Localization Organelle Localization Vesicle Docking Post-Golgi Vesicle-mediated Transport Protein Localization Membrane Organization Membrane Docking Long-term Synaptic Potentiation Regulation Of Protein Localization To Plasma Membrane Intracellular Protein Transport Positive Regulation Of Protein Localization To Cell Surface SNARE Complex Assembly Synaptic Transmission Positive Regulation Of Synaptic Transmission Regulation Of Protein Localization To Cell Surface Positive Regulation Of Regulated Secretory Pathway Cellular Protein Localization Transport Positive Regulation Of Peptidase Activity Response To Hydroperoxide Regulation Of Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Signaling Regulation Of Synaptic Plasticity Cell-cell Signaling Organelle Organization Positive Regulation Of Catalytic Activity Endoplasmic Reticulum Calcium Ion Homeostasis
Tagcloud ?		attachment cog cog4 cog8 defining ethylmalemide golgi gs27 initiate intermediates machinery namely oligomeric platforms redirection relocalization retrograde reveals snap29 snares sorting stx5 stx6 tethering tethers uncover vesicles vesicular vicinity	cellubrevin coimmunoprecipitation consistent cytoplasmic deleted domains glut1 glut4 immunoprecipitation insulin introduction membrane microinjection neither plasma recombinant requirement responsive resulted site snap stimulated syntaxin translocation vaccinia vamp2 vesicle vesicles
Tagcloud (Difference) ?		attachment cog cog4 cog8 defining ethylmalemide golgi gs27 initiate intermediates machinery namely oligomeric platforms redirection relocalization retrograde reveals snap29 snares sorting stx5 stx6 tethering tethers uncover vesicular vicinity	cellubrevin coimmunoprecipitation consistent cytoplasmic deleted domains glut1 glut4 immunoprecipitation insulin introduction membrane microinjection neither plasma recombinant requirement responsive resulted site snap stimulated syntaxin translocation vaccinia vamp2 vesicle
Tagcloud (Intersection) ?		vesicles