ASMTL and TDO2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		ASMTL	TDO2
Gene Name		acetylserotonin O-methyltransferase-like	tryptophan 2,3-dioxygenase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Cytosol
	Molecular Function	Molecular_function O-methyltransferase Activity	Tryptophan 2,3-dioxygenase Activity Amino Acid Binding Oxygen Binding Heme Binding Metal Ion Binding
	Biological Process	Biological_process Methylation	Tryptophan Catabolic Process Tryptophan Catabolic Process To Kynurenine Tryptophan Catabolic Process To Acetyl-CoA Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways			Tryptophan catabolism Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS			Speech perception in dyslexia ( 19786962)
Protein-Protein Interactions		7 interactors: APP HLA-DRB4 KRT31 KRT40 PNMA1 TDO2 UBC	15 interactors: ASMTL DPM1 EIF4E KDM1A MEOX2 MOB1A MOB3C NGB NMNAT1 PRMT6 PSMA1 REL SDCBP SDCBP2 ZFYVE26
Entrez ID		8623	6999
HPRD ID		02156	01847
Ensembl ID		ENSG00000169093	ENSG00000151790
Uniprot IDs		B3KM43 E7ER97 O95671	P48775
PDB IDs		2P5X
Enriched GO Terms of Interacting Partners?		Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Immune Response Defense Response Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway T Cell Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Tryptophan Catabolic Process To Acetyl-CoA Antigen Receptor-mediated Signaling Pathway Notch Signaling Pathway Innate Immune Response Collateral Sprouting In Absence Of Injury Immune System Process Intracellular Receptor Signaling Pathway Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Antigen Processing And Presentation Of Peptide Antigen Regulation Of Cell Cycle Phase Transition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Cycle Antigen Processing And Presentation Positive Regulation Of Proteolysis Neuron Remodeling Tryptophan Catabolic Process To Kynurenine Viral Protein Processing Kynurenine Metabolic Process
Tagcloud ?			agt ass1 beadchip benjamini crym differentiates egr2 folr3 gja1 hochberg hrasls humanref illumina leiomyosarcoma lms lmss masp1 nlgn1 nlgn4x ostn rorb shmt1 slitrk4 thbs1 tnnt1 tspan10 tspan7 uterine xrn2
Tagcloud (Difference) ?			agt ass1 beadchip benjamini crym differentiates egr2 folr3 gja1 hochberg hrasls humanref illumina leiomyosarcoma lms lmss masp1 nlgn1 nlgn4x ostn rorb shmt1 slitrk4 thbs1 tnnt1 tspan10 tspan7 uterine xrn2
Tagcloud (Intersection) ?