STC2 and FAF2

		STC2	FAF2
Description		stanniocalcin 2	Fas associated factor family member 2
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Perinuclear Region Of Cytoplasm	Extracellular Region Cytoplasm Endoplasmic Reticulum Lipid Droplet VCP-NPL4-UFD1 AAA ATPase Complex Azurophil Granule Lumen
	Molecular Function	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity	Protein Binding Protein-macromolecule Adaptor Activity Ubiquitin Protein Ligase Binding Lipase Binding Ubiquitin Binding Lipase Inhibitor Activity
	Biological Process	Intracellular Calcium Ion Homeostasis Response To Oxidative Stress Embryo Implantation Negative Regulation Of Gene Expression Endoplasmic Reticulum Unfolded Protein Response Response To Vitamin D Response To Endoplasmic Reticulum Stress Negative Regulation Of Multicellular Organism Growth Response To Peptide Hormone Decidualization Regulation Of Hormone Biosynthetic Process Calcium Ion Homeostasis Cellular Response To Hypoxia Regulation Of Store-operated Calcium Entry	Response To Unfolded Protein Proteasomal Protein Catabolic Process Retrograde Protein Transport, ER To Cytosol Lipid Droplet Organization Stress Granule Disassembly ERAD Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Neutrophil degranulation RHOA GTPase cycle
Drugs
Diseases
GWAS		A body shape index ( 34021172) Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Appendicular lean mass ( 33097823) Atrial fibrillation ( 29892015) Birth weight ( 31043758) Height ( 25429064 31562340) Hip circumference adjusted for BMI ( 34021172) Immunoglobulin A vasculitis ( 28698626) Prostate cancer ( 23535732) Retinitis pigmentosa ( 33514863) Urate levels in overweight individuals ( 25811787) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Cirrhosis (alcohol related) ( 32853455)
Interacting Genes		11 interacting genes: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 EIF2B3 PEBP1 POLR2C POLR3F PPP1R8 PTN	13 interacting genes: ELAVL1 FAF1 FAS MAP3K1 OGT PCAT1 PNPLA2 PSMD2 SMURF1 UBC UBE2D1 UBE3A VASP
Entrez ID		8614	23197
HPRD ID		04717	16870
Ensembl ID		ENSG00000113739	ENSG00000113194
Uniprot IDs		O76061 Q6FHC9	Q96CS3
PDB IDs		7Y5Q 8A7D 8A7E 8HGH	2DAM
Enriched GO Terms of Interacting Partners?			Fas Signaling Pathway Modification-dependent Protein Catabolic Process CD95 Death-inducing Signaling Complex Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Proteolysis Response To Nutrient Levels Positive Regulation Of Protein Metabolic Process Proteasomal Protein Catabolic Process Cytosol Catabolic Process Cellular Response To Nutrient Levels Ubiquitin-dependent Protein Catabolic Process Regulation Of TORC1 Signaling Regulation Of Protein Metabolic Process Macromolecule Catabolic Process Protein Catabolic Process Regulation Of TOR Signaling Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Autophagosome Size Positive Regulation Of Catabolic Process Glutamatergic Synapse Protein Metabolic Process Intracellular Chemical Homeostasis Sperm Entry Positive Regulation Of Golgi Lumen Acidification Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Engulfment Of Target By Autophagosome Regulation Of Post-translational Protein Modification Ubiquitin-protein Transferase Activity Protein Modification Process Proteasome Complex Positive Regulation Of Reactive Oxygen Species Metabolic Process Protein Ubiquitination Negative Regulation Of TORC1 Signaling TORC1 Signaling Positive Regulation Of TORC1 Signaling Negative Regulation Of BMP Signaling Pathway Protein Polyubiquitination Cellular Homeostasis Cellular Response To Mechanical Stimulus Regulation Of Stem Cell Population Maintenance Proteasome Storage Granule Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Protein Modification By Small Protein Conjugation Positive Regulation Of Metabolic Process Signal Transduction
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