STC2 and ADAM11

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		STC2	ADAM11
Description		stanniocalcin 2	ADAM metallopeptidase domain 11
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Perinuclear Region Of Cytoplasm	Plasma Membrane Membrane Axon Extracellular Matrix Presynaptic Membrane Cell Projection Perikaryon Synapse
	Molecular Function	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity	Metalloendopeptidase Activity Integrin Binding Metallopeptidase Activity
	Biological Process	Intracellular Calcium Ion Homeostasis Response To Oxidative Stress Embryo Implantation Negative Regulation Of Gene Expression Endoplasmic Reticulum Unfolded Protein Response Response To Vitamin D Response To Endoplasmic Reticulum Stress Negative Regulation Of Multicellular Organism Growth Response To Peptide Hormone Decidualization Regulation Of Hormone Biosynthetic Process Calcium Ion Homeostasis Cellular Response To Hypoxia Regulation Of Store-operated Calcium Entry	Proteolysis Integrin-mediated Signaling Pathway Multicellular Organismal Response To Stress Establishment Of Protein Localization Behavioral Response To Acetic Acid Induced Pain Behavioral Response To Formalin Induced Pain
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	LGI-ADAM interactions
Drugs
Diseases
GWAS		A body shape index ( 34021172) Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Appendicular lean mass ( 33097823) Atrial fibrillation ( 29892015) Birth weight ( 31043758) Height ( 25429064 31562340) Hip circumference adjusted for BMI ( 34021172) Immunoglobulin A vasculitis ( 28698626) Prostate cancer ( 23535732) Retinitis pigmentosa ( 33514863) Urate levels in overweight individuals ( 25811787) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		11 interacting genes: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 EIF2B3 PEBP1 POLR2C POLR3F PPP1R8 PTN	1 interacting genes: STC2
Entrez ID		8614	4185
HPRD ID		04717	01114
Ensembl ID		ENSG00000113739	ENSG00000073670
Uniprot IDs		O76061 Q6FHC9	B4DKD2 O75078
PDB IDs		7Y5Q 8A7D 8A7E 8HGH
Enriched GO Terms of Interacting Partners?			Decidualization Regulation Of Hormone Biosynthetic Process Response To Vitamin D Negative Regulation Of Multicellular Organism Growth Regulation Of Store-operated Calcium Entry Regulation Of Hormone Metabolic Process Embryo Implantation Endoplasmic Reticulum Unfolded Protein Response Regulation Of Multicellular Organism Growth Response To Vitamin Negative Regulation Of Developmental Growth
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