ZNF77 and RSPO4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF77	RSPO4
Description		zinc finger protein 77	R-spondin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Extracellular Space
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Signaling Receptor Binding Protein Binding Heparin Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Nail Development Limb Development Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		Generic Transcription Pathway	Regulation of FZD by ubiquitination
Drugs
Diseases			Anonychia congenita
GWAS		Chronic kidney disease ( 30226566) Coronary artery disease ( 30402224) Daytime sleep phenotypes ( 27126917) Ischemic stroke ( 29930801) Myocardial infarction ( 30226566)	Blood protein levels ( 30072576) Lean body mass ( 28552196) Logical memory (immediate recall) in Alzheimer's disease dementia ( 29274321)
Interacting Genes		7 interacting genes: FTO MBD3L1 METTL27 NICN1 PRDX3 RSPO4 RUSC1	15 interacting genes: ANKRD11 DHX57 GNG13 GPSM3 GUCD1 HGS KLHL38 LGR4 MAPK9 MKRN3 PIH1D2 STK16 USP20 ZNF330 ZNF77
Entrez ID		58492	343637
HPRD ID		08936	18788
Ensembl ID		ENSG00000175691	ENSG00000101282
Uniprot IDs		Q15935	Q2I0M5
PDB IDs
Enriched GO Terms of Interacting Partners?		NADH-dependent Peroxiredoxin Activity RNA Repair TRNA Demethylase Activity MRNA N6-methyladenosine Dioxygenase Activity
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