ZNF77 and METTL27

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF77	METTL27
Description		zinc finger protein 77	methyltransferase like 27
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Chronic kidney disease ( 30226566) Coronary artery disease ( 30402224) Daytime sleep phenotypes ( 27126917) Ischemic stroke ( 29930801) Myocardial infarction ( 30226566)
Interacting Genes		7 interacting genes: FTO MBD3L1 METTL27 NICN1 PRDX3 RSPO4 RUSC1	29 interacting genes: A1CF ATXN1 ATXN1L CCDC120 CSTF2 DOK6 EFHC1 ENKD1 FOXC2 GLYCTK GPANK1 GRB2 HGS KDM1A LMO4 NOXA1 PITX1 PRKAB2 PRMT6 PROP1 SAXO4 SNRPC TBX6 TEKT3 TFG TLX3 VPS37C ZIC1 ZNF77
Entrez ID		58492	155368
HPRD ID		08936	15661
Ensembl ID		ENSG00000175691	ENSG00000165171
Uniprot IDs		Q15935	Q8N6F8
PDB IDs
Enriched GO Terms of Interacting Partners?		NADH-dependent Peroxiredoxin Activity RNA Repair TRNA Demethylase Activity MRNA N6-methyladenosine Dioxygenase Activity	POZ Domain Binding Axonemal A Tubule Inner Sheath Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Sequence-specific Double-stranded DNA Binding Regulation Of Transcription By RNA Polymerase II Cell Fate Specification Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
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