ARID5A and GATA5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARID5A	GATA5
Description		AT-rich interaction domain 5A	GATA binding protein 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus	Chromatin Nucleus Nucleoplasm
	Molecular Function	Transcription Cis-regulatory Region Binding DNA Binding Chromatin Binding Transcription Corepressor Activity RNA Binding Protein Binding Transcription Factor Binding Nuclear Estrogen Receptor Binding RNA Stem-loop Binding MRNA 3'-UTR AU-rich Region Binding Identical Protein Binding Sequence-specific DNA Binding Nuclear Retinoid X Receptor Binding Nuclear Thyroid Hormone Receptor Binding Nuclear Androgen Receptor Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chondrocyte Differentiation Immune System Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Type II Interferon Production Positive Regulation Of Interleukin-17 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Innate Immune Response Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipopolysaccharide Cellular Response To Estrogen Stimulus Positive Regulation Of 3'-UTR-mediated MRNA Stabilization Positive Regulation Of T-helper 17 Type Immune Response Positive Regulation Of T-helper 1 Cell Cytokine Production	Negative Regulation Of Transcription By RNA Polymerase II Heart Induction Aortic Valve Morphogenesis Endocardial Cushion Fusion Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Heart Development Anatomical Structure Morphogenesis Tissue Development Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Differentiation Cell Fate Commitment Positive Regulation Of Notch Signaling Pathway Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Cardiac Muscle Tissue Development Intestinal Epithelial Cell Differentiation Positive Regulation Of Cardiac Endothelial To Mesenchymal Transition Cellular Response To Hydrogen Peroxide Cellular Response To Nitric Oxide Cellular Response To BMP Stimulus Positive Regulation Of Apoptotic DNA Fragmentation
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Eosinophil count ( 27863252 32888494) Eosinophil percentage of white cells ( 27863252 32888494) Event-related brain oscillations ( 21184583)	Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Central serous retinopathy ( 31872073) Chronic central serous retinopathy ( 30073298) Hematocrit ( 32888494) Hemoglobin ( 32888494) Prostate cancer ( 23535732)
Interacting Genes		127 interacting genes: ACTMAP ANKRD11 AR ATP6V0D2 ATXN1 ATXN1L BAG4 BAHD1 BANP BOLL C14orf119 CAMK2A CATSPER1 CCDC120 CCDC57 CKS1B COX5B CRYBA1 CRYBA2 CYSRT1 DAB1 DAZAP2 DOK6 DTX2 ESR2 ESRP1 FAM168B FHL3 FOXD2 FOXH1 GATA5 GLIS2 GOLGA2 GRB2 HDAC7 HOXA1 HSD3B7 INIP IRX6 KAZN KCTD9 KDF1 KRT40 KRTAP10-8 KRTAP12-2 KRTAP12-4 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP22-1 KRTAP26-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 LASP1 LENG8 LIMS3 LIMS4 LITAF LMO2 MAB21L2 MAGED1 MDFI MIEN1 MKRN3 MORN3 MYLIP NUDT22 ODAM OLIG3 OTX1 PHF1 PIBF1 PIN1 PITX1 PLA2G10 PLAGL2 PLEKHN1 PNMA1 POU1F1 PRDM6 PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E QRICH1 RARA RBFOX1 RBPMS RBPMS2 RFC5 RHOXF2 RNF44 ROR2 RXRA SEC24A SH2D2A SMYD1 SOHLH1 SOX5 TEKT3 TEKT4 TENT5A TENT5D TGM7 THRA TNS2 TRAF1 TRIM27 TRIM73 TSC1 TSEN15 TSSK3 UBTD2 USP20 VAC14 VENTX ZC3H10 ZIC1 ZNF503 ZNF765	10 interacting genes: ARID5A CYSRT1 EP300 HNF1A HPCA HPCAL1 KLF2 MAGED1 PLA2G10 PPARG
Entrez ID		10865	140628
HPRD ID		12481	17029
Ensembl ID		ENSG00000196843	ENSG00000130700
Uniprot IDs		Q03989	Q9BWX5
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription Cis-regulatory Region Binding Identical Protein Binding DNA-binding Transcription Factor Activity Nuclear Receptor Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of DNA-templated Transcription Nuclear Receptor-mediated Signaling Pathway Sequence-specific Double-stranded DNA Binding Regulation Of RNA Biosynthetic Process DNA Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway Positive Regulation Of Biosynthetic Process Sequence-specific DNA Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Spinal Cord Motor Neuron Migration POZ Domain Binding Regulation Of Gene Expression Chromatin Positive Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Nuclear Steroid Receptor Activity Retinoic Acid Receptor Signaling Pathway Regulation Of Metabolic Process Regulation Of Thyroid Hormone Receptor Signaling Pathway Regulation Of MRNA Metabolic Process Zinc Ion Binding Nucleus Retinoic Acid-responsive Element Binding Nuclear Protein Quality Control By The Ubiquitin-proteasome System	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of T-helper 17 Type Immune Response STAT Family Protein Binding Nuclear Retinoid X Receptor Binding Erythrocyte Maturation Cellular Response To Oxygen-containing Compound Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cell Maturation Regulation Of Transcription By RNA Polymerase II Nuclear Androgen Receptor Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Macrophage Derived Foam Cell Differentiation Chromatin Positive Regulation Of RNA Metabolic Process Developmental Maturation Regulation Of T-helper 17 Type Immune Response Transcription Coregulator Binding Response To Hormone Regulation Of Cholesterol Efflux Positive Regulation Of Nucleobase-containing Compound Metabolic Process Rhythmic Process Positive Regulation Of Transcription By RNA Polymerase II Long-chain Fatty Acid Transport Regulation Of Lipid Storage Transcription Cis-regulatory Region Binding Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Peptidyl-lysine Propionylation Regulation Of RNA Biosynthetic Process Swimming Histone Lactyltransferase (CoA-dependent) Activity Negative Regulation Of Macromolecule Biosynthetic Process Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Response To Estrogen Regulation Of Cholesterol Transport Positive Regulation Of Establishment Of Protein Localization Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Histone H2B Acetyltransferase Activity Regulation Of RNA Metabolic Process Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity
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