ARID5A and MIEN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARID5A	MIEN1
Description		AT-rich interaction domain 5A	migration and invasion enhancer 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus	Cytoplasm Mitochondrion Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane
	Molecular Function	Transcription Cis-regulatory Region Binding DNA Binding Chromatin Binding Transcription Corepressor Activity RNA Binding Protein Binding Transcription Factor Binding Nuclear Estrogen Receptor Binding RNA Stem-loop Binding MRNA 3'-UTR AU-rich Region Binding Identical Protein Binding Sequence-specific DNA Binding Nuclear Retinoid X Receptor Binding Nuclear Thyroid Hormone Receptor Binding Nuclear Androgen Receptor Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chondrocyte Differentiation Immune System Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Type II Interferon Production Positive Regulation Of Interleukin-17 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Innate Immune Response Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipopolysaccharide Cellular Response To Estrogen Stimulus Positive Regulation Of 3'-UTR-mediated MRNA Stabilization Positive Regulation Of T-helper 17 Type Immune Response Positive Regulation Of T-helper 1 Cell Cytokine Production	Apoptotic Process Positive Regulation Of Cell Migration Negative Regulation Of Apoptotic Process Positive Regulation Of Filopodium Assembly
Pathways
Drugs
Diseases
GWAS		Eosinophil count ( 27863252 32888494) Eosinophil percentage of white cells ( 27863252 32888494) Event-related brain oscillations ( 21184583)	Asthma ( 29273806 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Systemic lupus erythematosus ( 28714469)
Interacting Genes		127 interacting genes: ACTMAP ANKRD11 AR ATP6V0D2 ATXN1 ATXN1L BAG4 BAHD1 BANP BOLL C14orf119 CAMK2A CATSPER1 CCDC120 CCDC57 CKS1B COX5B CRYBA1 CRYBA2 CYSRT1 DAB1 DAZAP2 DOK6 DTX2 ESR2 ESRP1 FAM168B FHL3 FOXD2 FOXH1 GATA5 GLIS2 GOLGA2 GRB2 HDAC7 HOXA1 HSD3B7 INIP IRX6 KAZN KCTD9 KDF1 KRT40 KRTAP10-8 KRTAP12-2 KRTAP12-4 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP22-1 KRTAP26-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 LASP1 LENG8 LIMS3 LIMS4 LITAF LMO2 MAB21L2 MAGED1 MDFI MIEN1 MKRN3 MORN3 MYLIP NUDT22 ODAM OLIG3 OTX1 PHF1 PIBF1 PIN1 PITX1 PLA2G10 PLAGL2 PLEKHN1 PNMA1 POU1F1 PRDM6 PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E QRICH1 RARA RBFOX1 RBPMS RBPMS2 RFC5 RHOXF2 RNF44 ROR2 RXRA SEC24A SH2D2A SMYD1 SOHLH1 SOX5 TEKT3 TEKT4 TENT5A TENT5D TGM7 THRA TNS2 TRAF1 TRIM27 TRIM73 TSC1 TSEN15 TSSK3 UBTD2 USP20 VAC14 VENTX ZC3H10 ZIC1 ZNF503 ZNF765	15 interacting genes: ARID5A DDIT4L GORASP2 HDAC7 HIVEP1 HLX HMGB1 HMGB2 NLGN3 POU6F2 REL RNF126 TRIP6 VENTX ZBTB32
Entrez ID		10865	84299
HPRD ID		12481	12681
Ensembl ID		ENSG00000196843	ENSG00000141741
Uniprot IDs		Q03989	J3KTI2 Q9BRT3
PDB IDs			2LJK
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription Cis-regulatory Region Binding Identical Protein Binding DNA-binding Transcription Factor Activity Nuclear Receptor Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of DNA-templated Transcription Nuclear Receptor-mediated Signaling Pathway Sequence-specific Double-stranded DNA Binding Regulation Of RNA Biosynthetic Process DNA Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway Positive Regulation Of Biosynthetic Process Sequence-specific DNA Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Spinal Cord Motor Neuron Migration POZ Domain Binding Regulation Of Gene Expression Chromatin Positive Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Nuclear Steroid Receptor Activity Retinoic Acid Receptor Signaling Pathway Regulation Of Metabolic Process Regulation Of Thyroid Hormone Receptor Signaling Pathway Regulation Of MRNA Metabolic Process Zinc Ion Binding Nucleus Retinoic Acid-responsive Element Binding Nuclear Protein Quality Control By The Ubiquitin-proteasome System	DNA Binding Regulation Of Transcription By RNA Polymerase II DNA Geometric Change Supercoiled DNA Binding Regulation Of Interferon-beta Production Regulation Of Nucleobase-containing Compound Metabolic Process DNA Topological Change Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process RAGE Receptor Binding Regulation Of Cytokine Production Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process T-helper 1 Cell Differentiation Regulation Of Non-canonical NF-kappaB Signal Transduction DNA Binding, Bending DNA Conformation Change Four-way Junction DNA Binding V(D)J Recombination Transcription Factor Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Regulation Of Type I Interferon Production Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Nuclear Thyroid Hormone Receptor Binding Negative Regulation Of Alpha-beta T Cell Differentiation Regulation Of Primary Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of CD4-positive, Alpha-beta T Cell Activation Inflammatory Response To Antigenic Stimulus Chemoattractant Activity Condensed Chromosome Cellular Response To Lipopolysaccharide Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Sequence-specific DNA Binding T-helper Cell Differentiation Positive Regulation Of Interferon-beta Production DNA-binding Transcription Factor Binding Cellular Response To Molecule Of Bacterial Origin T Cell Differentiation Involved In Immune Response Positive Regulation Of Epithelial Cell Proliferation Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Somatic Cell DNA Recombination Positive Chemotaxis Transcription Corepressor Activity Negative Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process CD4-positive, Alpha-beta T Cell Differentiation Regulation Of Adaptive Immune Response
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