DLGAP2 and TSPOAP1

Number of citations of the paper that reports this interaction (PubMedID 24722188)
69

Data Source:
BioGRID (two hybrid)

		DLGAP2	TSPOAP1
Description		DLG associated protein 2	TSPO associated protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Neurofilament Plasma Membrane Postsynaptic Density Membrane Synapse Glutamatergic Synapse Postsynaptic Specialization	Cytoplasm Mitochondrion Cytosol Calyx Of Held Glutamatergic Synapse
	Molecular Function	Protein Binding Molecular Adaptor Activity	Protein Binding Benzodiazepine Receptor Binding Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels
	Biological Process	Neuron-neuron Synaptic Transmission Signaling Modulation Of Chemical Synaptic Transmission	Neuromuscular Synaptic Transmission Regulation Of Neurotransmitter Secretion Regulation Of Presynaptic Cytosolic Calcium Ion Concentration
Pathways			Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Pregnenolone biosynthesis Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Daytime nap ( 33568662) End-stage renal disease ( 29885931) Eye morphology ( 29921221) Femur bone mineral density x serum urate levels interaction ( 34046847) Lung cancer ( 28604730) Menarche (age at onset) ( 23599027) Neuritic plaque ( 31497858) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive astigmatism ( 30306274) Stroke ( 32693751) Tau burden ( 33426524) Triglycerides ( 24886709) White matter microstructure in first episode schizophrenia (right posterior cingulate cortex) ( 28924203)
Interacting Genes		18 interacting genes: ABI2 ADRB1 CYSRT1 DGCR6 DLG2 DLG4 DLGAP1 GRK5 KRT40 KRTAP4-2 MAGI2 NLGN4X NOS1 SHANK2 SHANK3 SORBS2 TSPOAP1 UBASH3B	19 interacting genes: ANKRD11 ARNT2 BEND5 CACNA1A CADPS2 CEP76 DISC1 DLGAP2 DLX2 GPRASP2 KHDRBS1 KIF1A MVP NDE1 RAPGEF4 REL TCF4 TSC22D4 TSPO
Entrez ID		9228	9256
HPRD ID		09258	09832
Ensembl ID		ENSG00000198010	ENSG00000005379
Uniprot IDs		A0A1B0GTN4	A7E2C5 B2RUT8 B7ZVZ7 O95153 X5DQQ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Postsynaptic Density Vocalization Behavior Ionotropic Glutamate Receptor Binding Receptor Clustering Synapse Social Behavior Dendritic Spine Scaffold Protein Binding Beta-1 Adrenergic Receptor Binding Synaptic Receptor Adaptor Activity AMPA Glutamate Receptor Clustering Modulation Of Chemical Synaptic Transmission Modulation Of Excitatory Postsynaptic Potential Learning Neuron Projection Cell Projection Synaptic Signaling Neuron Spine Photoreceptor Inner Segment Juxtaparanode Region Of Axon Regulation Of Membrane Potential Neurotransmitter-gated Ion Channel Clustering Cellular Response To Potassium Ion Postsynaptic Membrane Dendritic Spine Morphogenesis Kinase Binding Postsynaptic Density Membrane Learning Or Memory Calyx Of Held Response To Potassium Ion SH3 Domain Binding Cytoskeletal Anchor Activity Regulation Of System Process Regulation Of Nervous System Process Regulation Of Cell Communication Regulation Of Signaling Protein Localization To Membrane Chemical Synaptic Transmission Cognition Regulation Of The Force Of Heart Contraction Regulation Of Long-term Neuronal Synaptic Plasticity Cell-cell Signaling Trans-synaptic Signaling Signaling Excitatory Synapse Positive Regulation Of Synaptic Transmission Positive Regulation Of Excitatory Postsynaptic Potential Dendritic Spine Organization Adult Behavior Cell Communication	Kinesin Complex Synapse Secretory Granule Localization Establishment Of Vesicle Localization Vesicle Localization Glial Cell Migration Hematopoietic Stem Cell Homeostasis
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