DLGAP2 and NLGN4X

Number of citations of the paper that reports this interaction (PMID 11368788)
34

Data Source:
HPRD (in vitro)

		DLGAP2	NLGN4X
Gene Name		discs, large (Drosophila) homolog-associated protein 2	neuroligin 4, X-linked
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Neurofilament Postsynaptic Density Cell Junction Postsynaptic Membrane	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Postsynaptic Density Integral Component Of Membrane Cell Junction Dendrite Synapse Postsynaptic Membrane Excitatory Synapse
	Molecular Function	Protein Binding	Receptor Activity Protein Binding Chloride Ion Binding Neurexin Family Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding Carboxylic Ester Hydrolase Activity
	Biological Process	Neuron-neuron Synaptic Transmission	Brainstem Development Neuron Cell-cell Adhesion Learning Metabolic Process Cerebellum Development Neuron Differentiation Adult Behavior Social Behavior Organ Growth Cell-cell Junction Organization Regulation Of Synaptic Transmission Synapse Organization Vocalization Behavior Negative Regulation Of Excitatory Postsynaptic Membrane Potential Presynaptic Membrane Assembly
Pathways
Drugs
Diseases
GWAS		Menarche (age at onset) ( 23599027)
Protein-Protein Interactions		13 interactors: ADRB1 BZRAP1 DGCR6 DLG4 DLGAP1 GRK5 KRT40 KRTAP4-2 NLGN4X NOS1 SHANK2 SHANK3 SORBS2	2 interactors: DLG4 DLGAP2
Entrez ID		9228	57502
HPRD ID		09258	02336
Ensembl ID		ENSG00000198010	ENSG00000146938
Uniprot IDs		Q9P1A6	A8K4S1 B3KP11 Q8N0W4
PDB IDs			2WQZ 2XB6 3BE8
Enriched GO Terms of Interacting Partners?		Vocalization Behavior Social Behavior Regulation Of Postsynaptic Membrane Potential Synapse Assembly Learning Or Memory Synaptic Transmission Cognition Regulation Of Synaptic Transmission Learning Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Synapse Organization Single-organism Behavior Cell-cell Signaling Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Behavior Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Membrane Potential Positive Regulation Of Ion Transmembrane Transport Dendritic Spine Morphogenesis Positive Regulation Of Synaptic Transmission Membrane Depolarization Memory Dendritic Spine Development Regulation Of Ion Transmembrane Transport Dendritic Spine Organization Regulation Of Synaptic Plasticity Adult Behavior Exploration Behavior Postsynaptic Membrane Organization Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Ion Transport Regulation Of The Force Of Heart Contraction Neurological System Process Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Signaling Regulation Of Ion Transport Positive Regulation Of Membrane Potential Positive Regulation Of Lyase Activity Negative Regulation Of Blood Pressure Receptor Clustering Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Transporter Activity Negative Regulation Of Synaptic Transmission Regulation Of Cyclase Activity Positive Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of The Force Of Heart Contraction By Norepinephrine Regulation Of Cardiac Muscle Contraction Regulation Of Cation Channel Activity	Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Maintenance Of Apical/basal Cell Polarity Receptor Localization To Synapse Synaptic Transmission Negative Regulation Of Receptor Internalization Locomotory Exploration Behavior Dendritic Spine Morphogenesis Maintenance Of Cell Polarity Synaptic Vesicle Maturation Vocalization Behavior Dendritic Spine Development Protein Localization To Synapse Cell-cell Signaling Negative Regulation Of Receptor-mediated Endocytosis Dendritic Spine Organization Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Cortical Actin Cytoskeleton Organization Exploration Behavior Postsynaptic Membrane Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Cytoskeleton Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Receptor Internalization Positive Regulation Of Excitatory Postsynaptic Membrane Potential Golgi To Plasma Membrane Transport Synaptic Vesicle Endocytosis Synaptic Vesicle Recycling Social Behavior Positive Regulation Of Membrane Potential Negative Regulation Of Endocytosis Receptor Clustering Regulation Of Neuronal Synaptic Plasticity Nucleotide Phosphorylation Neuron-neuron Synaptic Transmission Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Neuromuscular Process Controlling Balance Synapse Assembly Dendrite Morphogenesis Post-Golgi Vesicle-mediated Transport Synaptic Vesicle Transport Positive Regulation Of Synaptic Transmission Membrane Depolarization Regulation Of Receptor Activity Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Neuromuscular Process Learning
Tagcloud ?		bell bgh bio blots bromo cnp deoxyuridine dor fibrillary gfap gh glul glutamine grin2a gs haemoglobin hbb igf1 igf1r inactivity ionotropic modestly phosphodiesterase postsynaptic robustly sapap2 synapse synthetase tg	agt ass1 beadchip benjamini crym differentiates egr2 folr3 gja1 hochberg hrasls humanref illumina leiomyosarcoma lms lmss masp1 nlgn1 ostn rorb shmt1 slitrk4 tdo2 thbs1 tnnt1 tspan10 tspan7 uterine xrn2
Tagcloud (Difference) ?		bell bgh bio blots bromo cnp deoxyuridine dor fibrillary gfap gh glul glutamine grin2a gs haemoglobin hbb igf1 igf1r inactivity ionotropic modestly phosphodiesterase postsynaptic robustly sapap2 synapse synthetase tg	agt ass1 beadchip benjamini crym differentiates egr2 folr3 gja1 hochberg hrasls humanref illumina leiomyosarcoma lms lmss masp1 nlgn1 ostn rorb shmt1 slitrk4 tdo2 thbs1 tnnt1 tspan10 tspan7 uterine xrn2
Tagcloud (Intersection) ?