NDUFB9 and SH3GL3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NDUFB9	SH3GL3
Gene Name		NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa	SH3-domain GRB2-like 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Extracellular Vesicular Exosome	Early Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	NADH Dehydrogenase (ubiquinone) Activity	Protein Binding Lipid Binding Identical Protein Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Sensory Perception Of Sound Respiratory Electron Transport Chain Cellular Metabolic Process Small Molecule Metabolic Process	Endocytosis Signal Transduction Central Nervous System Development
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs		NADH
Diseases
GWAS			Height ( 18391950 18391951 20397748)
Protein-Protein Interactions		10 interactors: FEZ1 GDF9 HAP1 IKBKAP IMMT MAGEA11 MEF2A RBBP6 SH3GL3 XRN1	44 interactors: ADRB1 AES ARHGDIA ARHGEF6 ATXN2 C11orf68 C4orf17 CALCOCO1 CBLC CD101 CRIP1 DNM1 DPPA4 DPYSL4 EGFL6 EMD FAM173A FASLG GABBR2 HTT LRRK2 NDUFB9 PDCD6IP PIAS4 PTPRO QTRT1 RBM48 RER1 RPL35A SEPT8 SH3D19 SH3GL1 SH3GL2 SH3KBP1 SHC3 SNRPN SNX24 SYNJ1 TERF1 TNNT1 TOE1 VIM WASL WDR33
Entrez ID		4715	6457
HPRD ID		03264	04528
Ensembl ID		ENSG00000147684	ENSG00000140600
Uniprot IDs		E9PF49 Q9Y6M9	Q99963
PDB IDs			2EW3 2Z0V
Enriched GO Terms of Interacting Partners?		Cellular Response To Growth Factor Stimulus Response To Growth Factor Mitochondrion Localization Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Positive Regulation Of Neurogenesis Organelle Localization Regulation Of Cell Projection Organization Regulation Of Dendrite Development Positive Regulation Of Cell Development Oocyte Growth Regulation Of Receptor Activity Positive Regulation Of Cilium Assembly ERK5 Cascade Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Secretion Regulation Of Progesterone Secretion Primary Heart Field Specification Sinoatrial Valve Morphogenesis Regulation Of Synaptic Activity Cellular Response To Trichostatin A Regulation Of Neurogenesis Ventricular Cardiac Myofibril Assembly Nephron Tubule Epithelial Cell Differentiation Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Muscle Cell Fate Determination Positive Regulation Of Cell Proliferation In Bone Marrow Nuclear MRNA Surveillance Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Behavioral Fear Response Neurotrophin Signaling Pathway RNA Surveillance Regulation Of Cell Development Positive Regulation Of Cell Differentiation Cellular Macromolecule Catabolic Process RNA Metabolic Process Cellular Response To Organic Substance Hypothalamus Cell Differentiation Histone MRNA Catabolic Process Anatomical Structure Development Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Homodimerization Activity Negative Regulation Of Beta-amyloid Formation Regulation Of Cellular Component Organization Positive Regulation Of Myeloid Cell Apoptotic Process	Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Signaling Regulation Of ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell-cell Signaling Signal Transduction Vesicle-mediated Transport Cell Communication Movement Of Cell Or Subcellular Component Regulation Of Vesicle-mediated Transport Response To Stimulus Cellular Response To Stimulus Cell Death Death Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Membrane Organization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuron Projection Morphogenesis Negative Regulation Of ERBB Signaling Pathway Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Developmental Process System Development Neuron Development Apoptotic Process Cellular Process Generation Of Neurons Actin Filament-based Movement Multicellular Organismal Development Nervous System Development Programmed Cell Death Regulation Of Signaling Neurogenesis Regulation Of Endocytosis Regulation Of Signal Transduction Negative Regulation Of Neuron Differentiation Neuron Projection Development Establishment Of Vesicle Localization Synaptic Transmission Positive Regulation Of Apoptotic Process Cell Projection Morphogenesis Neuron Differentiation Vesicle Localization Response To Growth Factor Axon Guidance Neurotrophin TRK Receptor Signaling Pathway Cell Part Morphogenesis
Tagcloud ?			85k aorta cbl cin85 circulation circulatory cooperation da diameters dorsal endocytosis exerted impairing interacting lumen lumens morpholino morpholinos partner phosphatidylinositol shrinkage shrunken specification stereotyped studying unaffected vasculature zebrafish
Tagcloud (Difference) ?			85k aorta cbl cin85 circulation circulatory cooperation da diameters dorsal endocytosis exerted impairing interacting lumen lumens morpholino morpholinos partner phosphatidylinositol shrinkage shrunken specification stereotyped studying unaffected vasculature zebrafish
Tagcloud (Intersection) ?