PPFIA4 and CAST

Number of citations of the paper that reports this interaction (PMID 12923177)
33

Data Source:
HPRD (in vitro, two hybrid)

		PPFIA4	CAST
Gene Name		protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	calpastatin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytosol Cell Surface Synapse Presynaptic Active Zone	Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding	Endopeptidase Inhibitor Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Poly(A) RNA Binding
	Biological Process	Synaptic Transmission Neurotransmitter Secretion Glutamate Secretion	Negative Regulation Of Endopeptidase Activity Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Pathways		Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs			Calcium
Diseases
GWAS			Alcohol dependence ( 19581569)
Protein-Protein Interactions		5 interactors: AGTPBP1 CAST ERC2 GIT1 NCOA2	10 interactors: CAPN1 CAPNS1 CASP1 CASP3 CASP7 HTRA1 PPFIA1 PPFIA2 PPFIA3 PPFIA4
Entrez ID		8497	831
HPRD ID		16012	00233
Ensembl ID		ENSG00000143847	ENSG00000153113
Uniprot IDs		B3KN22 O75335	P20810 Q59HE3 Q86YM9
PDB IDs
Enriched GO Terms of Interacting Partners?			Glutamate Secretion Acid Secretion Dicarboxylic Acid Transport Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Amino Acid Transport Neurotransmitter Transport Execution Phase Of Apoptosis Carboxylic Acid Transport Organic Acid Transport Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Extracellular Matrix Disassembly Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation Proteolysis Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Organic Anion Transport Positive Regulation Of Peptidase Activity Secretion By Cell Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Synaptic Transmission Regulation Of Cysteine-type Endopeptidase Activity Secretion Anion Transport Protein Processing Positive Regulation Of Proteolysis Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell-cell Signaling Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Endopeptidase Activity Regulation Of Peptidase Activity Mitochondrial Depolarization Positive Regulation Of Interleukin-1 Alpha Secretion Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Dentinogenesis Positive Regulation Of Cell Death Cell-matrix Adhesion Regulation Of Proteolysis Regulation Of Cell Proliferation Positive Regulation Of Interleukin-1 Alpha Production Pyroptosis Signaling Intrinsic Apoptotic Signaling Pathway Cell Communication Glial Cell Apoptotic Process
Tagcloud ?			absent antiserum b1 cardiomyocyte discs doubt dreifuss dystrophy edmd emerin emery explanation intercalated intranuclear lamin lamina lap1 lap2 lbr libraries localize mabs muscular myocyte nuclei phage recognize rim spots
Tagcloud (Difference) ?			absent antiserum b1 cardiomyocyte discs doubt dreifuss dystrophy edmd emerin emery explanation intercalated intranuclear lamin lamina lap1 lap2 lbr libraries localize mabs muscular myocyte nuclei phage recognize rim spots
Tagcloud (Intersection) ?