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FBXO18 and RAD51
Number of citations of the paper that reports this interaction (PMID
24108124
)
3
Data Source:
BioGRID
(pull down)
FBXO18
RAD51
Gene Name
F-box protein, helicase, 18
RAD51 recombinase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nuclear Chromosome
Condensed Chromosome
Condensed Nuclear Chromosome
Lateral Element
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Microtubule Organizing Center
PML Body
Perinuclear Region Of Cytoplasm
Molecular Function
DNA Binding
ATP-dependent DNA Helicase Activity
Protein Binding
ATP Binding
Damaged DNA Binding
Double-stranded DNA Binding
Single-stranded DNA Binding
Protein Binding
ATP Binding
Protein C-terminus Binding
Identical Protein Binding
Single-stranded DNA-dependent ATPase Activity
DNA Polymerase Binding
Biological Process
DNA Catabolic Process, Endonucleolytic
Positive Regulation Of Protein Phosphorylation
DNA Duplex Unwinding
Response To Intra-S DNA Damage Checkpoint Signaling
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Double-strand Break Repair Via Homologous Recombination
DNA Recombinase Assembly
DNA Unwinding Involved In DNA Replication
DNA Repair
Double-strand Break Repair
DNA Recombination
Mitotic Recombination
Cellular Response To DNA Damage Stimulus
Meiotic Nuclear Division
Reciprocal Meiotic Recombination
Regulation Of Double-strand Break Repair Via Homologous Recombination
Positive Regulation Of DNA Ligation
Protein Homooligomerization
Cellular Response To Ionizing Radiation
Cellular Response To Camptothecin
Pathways
Assembly of the RAD51-ssDNA nucleoprotein complex
Homologous DNA pairing and strand exchange
Meiotic recombination
Homologous Recombination Repair
Homologous recombination repair of replication-independent double-strand breaks
Double-Strand Break Repair
Presynaptic phase of homologous DNA pairing and strand exchange
Drugs
Diseases
GWAS
Breast cancer (
20453838
)
Protein-Protein Interactions
8 interactors:
CUL1
PIM2
RAD51
RBX1
RPL13A
SKP1
UBC
ZDHHC17
42 interactors:
ABL1
ATM
ATRX
BCCIP
BLM
BRCA1
BRCA2
CASP3
CASP7
CHD3
CHEK1
DMC1
DNAJA3
ERCC2
FANCD2
FBXO18
HID1
HNRNPC
IRS1
MDC1
NXF1
PFN1
RAD18
RAD51AP1
RAD51AP2
RAD51C
RAD52
RAD54B
RAD54L
RPA1
RPA3
SFR1
SUMO1
SWI5
SWSAP1
TP53
UBE2I
UGDH
UHRF2
VIM
WRN
ZDHHC17
Entrez ID
84893
5888
HPRD ID
06243
01557
Ensembl ID
ENSG00000134452
ENSG00000051180
Uniprot IDs
B3KV95
Q2TAK1
Q8NFZ0
Q06609
PDB IDs
1B22
1N0W
Enriched GO Terms of Interacting Partners
?
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Notch Signaling Pathway
G1/S Transition Of Mitotic Cell Cycle
Protein Monoubiquitination
Viral Process
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Cellular Macromolecule Catabolic Process
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
G2/M Transition Of Mitotic Cell Cycle
Cell Cycle Process
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Circadian Rhythm
Protein Ubiquitination
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Protein Catabolic Process
Protein Modification By Small Protein Conjugation
Cell Cycle
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Catabolic Process
Mitotic Cell Cycle Process
Cellular Protein Metabolic Process
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Mitotic Cell Cycle
Positive Regulation Of Proteolysis
Rhythmic Process
Catabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Cellular Protein Modification Process
Regulation Of DNA-templated Transcription In Response To Stress
Response To Stimulus
Regulation Of Protein Catabolic Process
Protein Metabolic Process
Negative Regulation Of Formation Of Translation Preinitiation Complex
DNA Metabolic Process
DNA Repair
Cellular Response To DNA Damage Stimulus
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
Double-strand Break Repair
DNA Recombination
Cellular Response To Stress
Response To Stress
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Response To Radiation
Cellular Nitrogen Compound Metabolic Process
Chromosome Organization
Response To Ionizing Radiation
Organelle Organization
Cell Cycle
Nitrogen Compound Metabolic Process
Cellular Response To Stimulus
DNA Duplex Unwinding
DNA Geometric Change
Response To Abiotic Stimulus
Regulation Of Cell Cycle
Response To Stimulus
Cell Cycle Process
DNA-dependent DNA Replication
DNA Replication
Signal Transduction In Response To DNA Damage
Meiotic Nuclear Division
Cellular Response To Ionizing Radiation
DNA Conformation Change
Positive Regulation Of Cell Cycle
Regulation Of Mitotic Cell Cycle
Cell Aging
Response To UV
Meiotic Cell Cycle
Cellular Response To Radiation
DNA Catabolic Process
DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Cell Cycle Process
Cellular Metabolic Process
Replication Fork Processing
Cellular Response To Hydroxyurea
Intrinsic Apoptotic Signaling Pathway
Meiosis I
Response To Gamma Radiation
Signal Transduction By P53 Class Mediator
DNA Recombinase Assembly
Regulation Of Response To DNA Damage Stimulus
Tagcloud
?
boundary
box
cerevisiae
consisting
damaging
declined
delta
dosage
dsc1
elements
enhances
fluctuate
fluctuation
frequency
mbf1
mbp1
mcb
meiosis
meiotic
mitotic
mlu
rad54
recombination
saccharomyces
spore
sporulation
swi6
transcript
viability
Tagcloud (Difference)
?
boundary
box
cerevisiae
consisting
damaging
declined
delta
dosage
dsc1
elements
enhances
fluctuate
fluctuation
frequency
mbf1
mbp1
mcb
meiosis
meiotic
mitotic
mlu
rad54
recombination
saccharomyces
spore
sporulation
swi6
transcript
viability
Tagcloud (Intersection)
?