FBXO18

Gene Name		F-box protein, helicase, 18
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	DNA Binding ATP-dependent DNA Helicase Activity Protein Binding ATP Binding
	Biological Process	DNA Catabolic Process, Endonucleolytic Positive Regulation Of Protein Phosphorylation DNA Duplex Unwinding Response To Intra-S DNA Damage Checkpoint Signaling Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 20453838)
Protein-protein Interactions		8 interactors: CUL1 PIM2 RAD51 RBX1 RPL13A SKP1 UBC ZDHHC17
Entrez ID		84893
HPRD ID		06243
Ensembl ID		ENSG00000134452
Uniprot IDs		B3KV95 Q2TAK1 Q8NFZ0
PDB IDs
Enriched GO Terms of Interacting Partners?		SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Notch Signaling Pathway G1/S Transition Of Mitotic Cell Cycle Protein Monoubiquitination Viral Process Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Cellular Macromolecule Catabolic Process Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process G2/M Transition Of Mitotic Cell Cycle Cell Cycle Process Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Circadian Rhythm Protein Ubiquitination Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein Catabolic Process Protein Modification By Small Protein Conjugation Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Protein Ubiquitination Positive Regulation Of Protein Catabolic Process Mitotic Cell Cycle Process Cellular Protein Metabolic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Mitotic Cell Cycle Positive Regulation Of Proteolysis Rhythmic Process Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Cellular Protein Modification Process Regulation Of DNA-templated Transcription In Response To Stress Response To Stimulus Regulation Of Protein Catabolic Process Protein Metabolic Process Negative Regulation Of Formation Of Translation Preinitiation Complex
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