PHF5A and PRPF31

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		PHF5A	PRPF31
Gene Name		PHD finger protein 5A	pre-mRNA processing factor 31
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm U2 SnRNP U12-type Spliceosomal Complex Nuclear Matrix Nuclear Speck	Nucleus U2-type Spliceosomal Complex U4 SnRNP U4atac SnRNP Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex MLL1 Complex
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Poly(A) RNA Binding	Protein Binding Ribonucleoprotein Complex Binding Poly(A) RNA Binding SnRNP Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription, DNA-templated RNA Splicing Gene Expression Positive Regulation Of Transcription, DNA-templated	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: FOXB1 PRPF31 ZDHHC17	55 interactors: AES C1QTNF1 CALCOCO2 CCDC136 CCDC57 CDCA7L CEP70 FANCA GNB2L1 GOLGA2 HNRNPH2 HNRNPK JAKMIP2 KCTD6 KHDRBS2 KHDRBS3 KRT15 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-8 KRTAP10-9 LDOC1 LURAP1 MID2 MIPOL1 MKRN3 MTUS2 NHP2L1 NOTCH2NL PDE4DIP PHC2 PHF5A PNMA1 PNMA2 PPIH PRICKLE1 PRPF3 PRPF4 PSTPIP1 RBM25 RBM4 RBMY1A1 RBMY1F SIAH1 SSX2IP STX11 TADA2A TFIP11 TMCC2 TP53BP2 TRIM27 TSGA10 ZNF250 ZNF587
Entrez ID		84844	26121
HPRD ID		15126	05917
Ensembl ID		ENSG00000100410	ENSG00000105618
Uniprot IDs		Q7RTV0	E7ESA8 F1T0A4 F1T0A5 Q8WWY3
PDB IDs			2OZB 3SIU 3SIV
Enriched GO Terms of Interacting Partners?		Mammillothalamic Axonal Tract Development Cell Migration In Diencephalon Mammillary Body Development Inferior Colliculus Development Axon Target Recognition Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Hypothalamus Cell Migration Floor Plate Development Spliceosomal Tri-snRNP Complex Assembly Thalamus Development Lipoprotein Transport Magnesium Ion Transport Mammary Gland Epithelial Cell Differentiation Hypothalamus Development Protein Palmitoylation Spliceosomal SnRNP Assembly Mammary Gland Alveolus Development Mammary Gland Lobule Development	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Spermatogenesis Male Gamete Generation Negative Regulation Of Viral Release From Host Cell Regulation Of Gene Expression Regulation Of MRNA Processing Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of RNA Splicing Gamete Generation Protein Trimerization Spliceosomal Complex Disassembly Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Reproduction Sexual Reproduction Regulation Of Viral Process Multicellular Organismal Reproductive Process Regulation Of RNA Metabolic Process Multicellular Organism Reproduction Regulation Of Nitrogen Compound Metabolic Process Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Interleukin-2 Secretion Positive Regulation Of Aldosterone Secretion Positive Regulation Of CAMP Catabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of Protein Binding Positive Regulation Of Cell Death Single Organism Reproductive Process Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Cellular Component Assembly
Tagcloud ?		aiming aip alignment boar brms1 chordc1 clues cops6 csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h	ala78leufsx99 amplified autosomal chinese exons families frequencies harbor heterozygous hong kong missense modify nonpathogenic phe262serfsx59 pigmentosa pro347leu prph2 retina retinitis rho screen screened simplex stranded thirteen truncating woman
Tagcloud (Difference) ?		aiming aip alignment boar brms1 chordc1 clues cops6 csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h	ala78leufsx99 amplified autosomal chinese exons families frequencies harbor heterozygous hong kong missense modify nonpathogenic phe262serfsx59 pigmentosa pro347leu prph2 retina retinitis rho screen screened simplex stranded thirteen truncating woman
Tagcloud (Intersection) ?