PLPP7 and PRRC2B

		PLPP7	PRRC2B
Description		phospholipid phosphatase 7 (inactive)	proline rich coiled-coil 2B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Sphingosine-1-phosphate Phosphatase Activity	RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Myotube Differentiation	Cell Differentiation
Pathways
Drugs
Diseases
GWAS		PR interval ( 32439900)	Femur bone mineral density x serum urate levels interaction ( 34046847) Lung function ( 31902109) Urate levels ( 31578528)
Interacting Genes		1 interacting genes: SMO	41 interacting genes: ALG13 ANKHD1 APP ATN1 ATXN1 ATXN1L BAG4 BCAS2 CRK CTBP1 DAPK1 DDX11 DIMT1 DMRTB1 DNAJC5 DPY30 EHMT2 ESS2 EXOSC1 EXOSC4 EXOSC7 FBXO7 IPO5 LSM5 MRPL44 NIP7 NXF1 NXF5 PRPF39 QKI RBFOX2 RBPMS RERE RPL13 SF1 SRPK2 SRSF4 TRNAU1AP TXNL4A YTHDF1 YTHDF3
Entrez ID		84814	84726
HPRD ID		12972	13805
Ensembl ID		ENSG00000160539	ENSG00000288701
Uniprot IDs		A0A384NPM3 Q8NBV4 X6R886	Q5JSZ5 Q9BU62
PDB IDs
Enriched GO Terms of Interacting Partners?		Mesenchymal To Epithelial Transition Involved In Metanephric Renal Vesicle Formation Ventral Midline Determination Contact Inhibition Determination Of Left/right Asymmetry In Lateral Mesoderm Commissural Neuron Axon Guidance Thalamus Development Cerebellar Cortex Morphogenesis Cellular Response To Cholesterol Spinal Cord Dorsal/ventral Patterning Somite Development Detection Of Cell Density CAMP-dependent Protein Kinase Inhibitor Activity Midgut Development Epithelial-mesenchymal Cell Signaling Regulation Of Somatic Stem Cell Population Maintenance Pancreas Morphogenesis Mesenchymal To Epithelial Transition Response To Inositol Myoblast Migration Left/right Axis Specification Atrial Septum Morphogenesis Dorsal/ventral Neural Tube Patterning Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Patched Binding 9+0 Non-motile Cilium Oxysterol Binding Protein Kinase A Catalytic Subunit Binding Negative Regulation Of Hair Follicle Development Forebrain Morphogenesis Regulation Of Heart Morphogenesis Type B Pancreatic Cell Development Mammary Gland Epithelial Cell Differentiation Negative Regulation Of DNA Binding Astrocyte Activation Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Cellular Response To Sterol Regulation Of Hair Follicle Development Smooth Muscle Tissue Development Regulation Of Branching Involved In Ureteric Bud Morphogenesis Regulation Of Hair Cycle Dentate Gyrus Development Response To Cholesterol Plasma Membrane Bounded Cell Projection Skeletal Muscle Fiber Development Positive Regulation Of Neuroblast Proliferation Positive Regulation Of Mesenchymal Cell Proliferation Muscle Cell Migration Detection Of Biotic Stimulus Cell Differentiation Involved In Kidney Development Hair Follicle Morphogenesis	RNA Binding Nucleus RNA Processing RNA Metabolic Process Nucleic Acid Binding RNA Splicing MRNA Metabolic Process Nucleolus MRNA Processing MRNA Binding Nucleoplasm Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Splicing, Via Transesterification Reactions Nucleolar Exosome (RNase Complex) Regulation Of MRNA Metabolic Process Cytoplasmic Stress Granule Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity Macromolecule Metabolic Process Regulation Of RNA Splicing Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Regulation Of MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing POZ Domain Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Stress Granule Assembly Negative Regulation Of Macromolecule Metabolic Process MRNA Splice Site Recognition Exoribonuclease Complex Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Spliceosomal Complex Nuclear RNA Export Factor Complex U4 SnRNA 3'-end Processing Protein-RNA Complex Assembly Cytoplasm Transcription Corepressor Activity Negative Regulation Of Metabolic Process Spliceosomal Complex Assembly Memory Negative Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Nuclear MRNA Surveillance Nuclear Inclusion Body N6-methyladenosine-containing RNA Reader Activity
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